… the crystal packing arrangements in the presently available MBP and MBP fusion protein crystal
structures … protruding out furthest from the globular structure of MBP (around residues 83, …

… adopts a loop similar to that seen in the crystal structure. We therefore investigated the
importance of the cyclic conformation for high affinity LPS binding. We synthesized several cyclic …

… We report here the crystal structure of one such intermediate species, namely, horse
deoxyhaemoglobin in the R state, at 1.8 Å resolution. While ligand binding in the T state may result …

… affinity for jeffamine. Moreover, a comparison of the crystal structures of the germline and
affinity… primitive proteins, to evolve high affinity, selective receptors for so many distinct chemical …

… We have solved the crystal structure of another in vitro affinity enhanced TCR which binds
to … Like the high affinity 1G4 described in this paper, this high affinity TCR bound pMHC in a …

… extremely high affinities towards the vitamin d-biotin (Green, 1975, 1990). The tetrameric
structure of the proteins is essential for their high affinity for biotin. The high affinity between …

… The crystal structure of 2 in complex with TGT demonstrates … The crystal structure of
unsubstituted lin-benzoguanine in … Here, we present affinity data and crystallographic results of the …

… of the high affinity CD8 mutant using surface plasmon resonance and determined its structure
at 2.1 … To engineer a form of CD8 αα with higher affinity for pHLA I, we designed a series of …

… Compared to a recent NMR structure of a similar complex, our crystal structure reveals an …
we compare our crystal structure with the recently published βPIX/Cbl-b complex structure, and …

… contact residues, a detailed structural interpretation of the increased binding affinity of this
variant will have to await determination of the crystal structure of the complex with the receptor. …