Structural basis of high-affinity glycan recognition by bacterial and fungal lectins
A Imberty, EP Mitchell, M Wimmerová - Current opinion in structural biology, 2005 - Elsevier
… The novelty of the new structures is greater at the level of the sugar-binding sites, with
some bacterial lectins displaying unusually high affinity for oligosaccharides and even …
some bacterial lectins displaying unusually high affinity for oligosaccharides and even …
Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding
J Lu, J Chu, Z Zou, NB Hamacher… - Proceedings of the …, 2015 - National Acad Sciences
… We report the first structure of the high-affinity Fc receptor in … recognition of Fc glycan as
a major factor in receptor affinity. This is the first example of Fc receptor making direct glycan …
a major factor in receptor affinity. This is the first example of Fc receptor making direct glycan …
The challenges of glycan recognition with natural and artificial receptors
S Tommasone, F Allabush, YK Tagger… - Chemical Society …, 2019 - pubs.rsc.org
… recognition of glycans by other molecules with high affinity … a whole the field of glycan
recognition, identify key challenges … on creating glycan-binding scaffolds with high affinity and, …
recognition, identify key challenges … on creating glycan-binding scaffolds with high affinity and, …
Glycan‐based high‐affinity ligands for toxins and pathogen receptors
AA Kulkarni, AA Weiss, SS Iyer - Medicinal research reviews, 2010 - Wiley Online Library
… RECEPTOR RECOGNITION When compared to genomics or proteomics, glycan recognition
… (ii) Competition experiments between two glycans will identify the higher affinity glycan (ii) …
… (ii) Competition experiments between two glycans will identify the higher affinity glycan (ii) …
Glycan: glycan interactions: high affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells
… Escherichia coli type 1 fimbriae, FimH, is one of the most widely studied glycan-recognizing
protein … Other glycan-recognizing adhesins expressed by bacteria include the following: …
protein … Other glycan-recognizing adhesins expressed by bacteria include the following: …
Stereoelectronic effects impact glycan recognition
… 1-phosphate, are the most relevant ligands from the observed glycan array hits. They are
bound by hItln-1 with higher affinity than the heptoses. The weaker inhibitory activities of l,d-…
bound by hItln-1 with higher affinity than the heptoses. The weaker inhibitory activities of l,d-…
High-affinity anti-glycan antibodies: challenges and strategies
… the number of potential molecular targets in cancer and infectious diseases by opening a
wider world of carbohydrate structures to immunological recognition and high-affinity response. …
wider world of carbohydrate structures to immunological recognition and high-affinity response. …
[HTML][HTML] MCAW-DB: A glycan profile database capturing the ambiguity of glycan recognition patterns
M Hosoda, Y Takahashi, M Shiota, D Shinmachi… - Carbohydrate …, 2018 - Elsevier
… For MCAW-DB, we selected 1081 glycan datasets from CFG under the … high-affinity glycans
and none of them were monosaccharides. We used those glycans that have high affinity to …
and none of them were monosaccharides. We used those glycans that have high affinity to …
Virus recognition of glycan receptors
… recognize proteoglycans with extended glycan chains of up … detailed specificity of virus–glycan
recognition in these cases is … whose own glycans are recognized by host glycan-binding …
recognition in these cases is … whose own glycans are recognized by host glycan-binding …
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
H Mouquet, L Scharf, Z Euler, Y Liu… - Proceedings of the …, 2012 - National Acad Sciences
… glycan recognition by PGT121-like antibodies from a crystal structure in which a complex-type
sialylated N-glycan … The glycan corresponds to the α2–6 sialylated glycan that PGT121 …
sialylated N-glycan … The glycan corresponds to the α2–6 sialylated glycan that PGT121 …
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