… We also demonstrate that the anchor residues in class II bindingpeptides are additive and
… in a pool of DR-binding peptides selected from a large, phageexpressed random peptide …

… clamping of the intermediate into the high-affinity complex. … and the partial affinity triggered
by anchoring interactions are … cementing the high-affinity complex would be larger than that …

… , the peptides do not insert any large anchor residues into the binding pockets of the
shallow IA d binding groove. The previously identified six-residue “core” binding motif of IA d …

… It is possible that the insertion of large amino acids at the anchor position might have forced
the peptide to roll or shift register in the binding groove.) In this analysis, the anchor residue …

… anchor has highest affinity for hIgG1 but lowest affinity for … with a full anchor, other,
nonconserved residues may interact … in 2D affinity of the CD16-IgG binding has a large effect on …

… In this paper, large … and anchor residues are important for A2.1 binding capacity, the following
analysis was performed. We reasoned that amino acid residues that facilitated high affinity …

… anchor residues are necessary for highaffinity binding, and that high-affinity binding occurs
only when anchor … bution of two anchor side chains to binding is unexpectedly large and …

… Two known HLA-All-restricted cytotoxic T-lymphocyte epitope peptides showed high affinity
… study using a large number of peptides carrying the anchor residues and mutated peptides …

… alpha chain residues 114, 147, 152 and 156, but larger P7 … anchor residues endows a
peptide with high affinity to an MHC molecule in the absence of one of the primary anchor residues…

… It is applicable to test a large number of HLA allelic products … confirmed the high allele
specificity of the anchor residue … of high-affinity and/or abundant peptides and also of high HLA …