… of interferon with the cell surface requires direct ligand-binding studies. I present here direct
evidence that highaffinity binding of interferon to a specific cell surface receptor is an initial …

… cells. This paper describes the use of recombinant murine BSF-1, radiolabeled with 1251Ito
high specific activity, to study the cellular … of the receptor. This initial characterization of the …

… 5a) all strongly suggest that the specific receptor for mouse cx and /3 … a high affinity to a cell
surface receptor. The biologic response depends quantitatively on the degree of receptor site …

… Cell lines of human and mouse origin differ in their sensitivity to the cytotoxic/ cytostatic effect
of TNF (1, 5-7) and cells … we demonstrate the existence of cell surface receptors to TNF and …

… lipoprotein (LDL) cell surface receptors on human fibroblasts … (1,2) but also certain specific
high density lipoproteins (HDL) … for high affinity binding to the cell surface receptor (7). …

… HSPGs and heparin-like sequences are indeed specific for different heparin-binding
growth factors and constitute a discrete class of low affinity membrane receptors. HSPGs are …

… A variety of normal and transformed avian and mammalian cells and tissues contain high
affinity specific receptors on their membranes which interact with biologically active phorbol …

… hormone to surface receptors, because the addition of specific, … only a negligible fraction of
very high affinity binding sites. Thus, the … and persistent occupation of cell surface receptors. …

… procedure is shown in this study to bind specifically to high-affinity cell surface receptors.
Cells of several different sources are shown to exhibit such binding: fibroblasts (the FS-11 …

… may affect cellular regulation through cell surface receptors. It … TN-C, as soluble ligands, bind
to receptors on the cell surface. … the specific binding of native TN-C to endothelial cells and …