… In hypertension (HTN), cerebral blood flow regulation limits are changed, and the threshold
for blood pressure … We investigated whether longitudinal reduction in mean arterial pressure (…

… , but also a potential modulator of tau pathologies. Therefore, we further explored whether
tau pathologies could mediate the influences of hypertension on cognition. The results …

… blood pressure (BP) may alleviate AD-type Aβ neuropathology and neurological disorders
associated with abnormal tau … of pathological tau species found in control P301L-tau Tg …

… and declining slope of systolic blood pressure with each of the … (B) Associations for diastolic
blood pressure with the same … Pulse pressure in relation to tau-mediated neurodegeneration…

… neuropathological changes that link hypertension to AD remain poorly … hypertension and
high current blood pressure (BP) with in vivo AD pathologies including β-amyloid (Aβ) and tau …

… between FRS and Aβ in relation to tau pathology, we separately examined each of the five
components of FRS. In each of the five linear regressions with tau levels as the outcome, one …

… We did this because of its high correlation with systolic blood pressure and to disambiguate
… amyloid and tau pathologies. This possibility is further supported by the fact that higher pulse …

… Tau PET may be used to detect changes over months to years in tau pathology, whereas
CSF T-tau and P-tau may be used to monitor changes in the neuronal release pattern of these …

… Additional variables related to blood pressure were also measured at baseline and annually…
role in tau pathologic change. It is well documented that β-amyloid drives tau accumulation …

… tau pathology, we examined the correlation between the severity of arteriosclerosis and
neurofibrillary tangle pathology in … measures of hypertensive blood pressure are associated with …