Continuous administration of polyphenols from aqueous rooibos (Aspalathus linearis) extract ameliorates dietary-induced metabolic disturbances in hyperlipidemic …

R Beltrán-Debón, A Rull, F Rodríguez-Sanabria… - Phytomedicine, 2011 - Elsevier
… compounds in rooibos extract and found that the continuous administration of this extract has
no … absorption as an explanation for such a net reduction in fat storage cannot be ruled out …

[HTML][HTML] Aspalathin-rich green rooibos extract lowers LDL-cholesterol and oxidative status in high-fat diet-induced diabetic vervet monkeys

P Orlando, N Chellan, J Louw, L Tiano, I Cirilli… - Molecules, 2019 - mdpi.com
… In this study, high-fat diet-induced diabetic and non-diabetic vervet monkeys were treated
with 90 mg/kg of aspalathin-rich green rooibos extract (Afriplex GRT) for 28 days, followed by a …

The modulating effects of green rooibos (Aspalathus linearis) extract on vascular function and antioxidant status in obese Wistar rats

Z Obasa, MA van Vuuren, B Huisamen… - … Journal of Africa, 2021 - journals.co.za
… 19,26 and excess consumption of a high-fat, highsugar diet has been previously shown as a
… HFD animals contributed to their higher body weight, leptin levels, and IP fat and liver mass (…

Effects of fermented rooibos (Aspalathus linearis) on adipocyte differentiation

M Sanderson, SE Mazibuko, E Joubert, D de Beer… - Phytomedicine, 2014 - Elsevier
… , extracted from fermented rooibos during the … rooibos extract (Beltrán-Debón et al., 2011).
These authors established the hypolipidemic effect of rooibos in LDLr −/− mice fed a high fat

A histomorphometric study on the hepatoprotective effects of a green rooibos extract in a diet-induced obese rat model

JI Layman, DL Pereira, N Chellan, B Huisamen… - Acta histochemica, 2019 - Elsevier
… evaluate the ameliorative effects of an unfermented green rooibos extract (GRE) on liver tissue
in … A comparison of the control and high-fat diets in terms of the percentage contribution of …

[HTML][HTML] Aspalathin-enriched green rooibos extract reduces hepatic insulin resistance by modulating PI3K/AKT and AMPK pathways

SE Mazibuko-Mbeje, PV Dludla, C Roux… - International journal of …, 2019 - mdpi.com
… Therefore, this study used palmitate to induce insulin resistance in C3A cells and a high-fat,
high-sugar diet to induce obesity and insulin resistance in Wistar rats. Thereafter, the …

Anti-oxidative effects of rooibos tea extract on autoxidation and thermal oxidation of lipids

R Fukasawa, A Kanda, S Hara - Journal of Oleo Science, 2009 - jstage.jst.go.jp
… contained in rooibos tea … extracts and powdered rooibos tea extract (RTE) made by
freeze-drying; these substances were examined by autoxidation tests with high linoleic safflower fatty-…

[HTML][HTML] Aspalathin from rooibos (Aspalathus linearis): a bioactive C-glucosyl dihydrochalcone with potential to target the metabolic syndrome

R Johnson, D de Beer, PV Dludla, D Ferreira… - Planta …, 2018 - thieme-connect.com
… relevant biological activity of extracts prepared from green rooibos, containing high levels of
… (12.8% aspalathin content) administered at 90 mg/kg three times daily with meals to high-fat

Potential of rooibos, its major C-glucosyl flavonoids, and Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome

CJF Muller, CJ Malherbe, N Chellan… - Critical Reviews in …, 2018 - Taylor & Francis
… of the antidiabetic properties of rooibos extracts, the current … use of rooibos as herbal tea and
food ingredient extract, its … hypolipidemic effect for rooibos in LDLr-/- mice fed a high fat diet, …

[HTML][HTML] Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice

O Patel, CJF Muller, E Joubert, B Rosenkranz, J Louw… - PloS one, 2021 - journals.plos.org
… However, the treatment efficacy of rooibos extract in combination with conventional … This
study aimed to investigate the effects of combining an aspalathin-rich green rooibos extract (…