Glucose metabolism and cardiac hypertrophy

SC Kolwicz Jr, R Tian - Cardiovascular research, 2011 - academic.oup.com
… reduced glucose utilization have demonstrated that glucose reliance in the adult heart is not
harmful while reduced ability to utilize glucose is detrimental in cardiac hypertrophyglucose

Glucose metabolism in cardiac hypertrophy and heart failure

DH Tran, ZV Wang - Journal of the American Heart Association, 2019 - Am Heart Assoc
… may lead to an even higher level of lactate and lower rate of glucose oxidation. Collectively,
cardiac hypertrophy, increased glycolysis may be accompanied by uncoupling of glucose

[HTML][HTML] Glucose transporters in cardiac metabolism and hypertrophy

D Shao, R Tian - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
… and translocation; the mechanisms involved in the regulation of glucose uptake into
cardiomyocytes and discuss changes of glucose metabolism in pathological cardiac hypertrophy. …

Insulin resistance in patients with cardiac hypertrophy

G Paternostro, D Pagano… - Cardiovascular …, 1999 - academic.oup.com
… insulin was shown to be higher in hypertrophied hearts compared to controls. No other human
studies of myocardial glucose uptake in global cardiac hypertrophy have been published. …

High glucose induces cardiac insulin-like growth factor I resistance in ventricular myocytes: role of Akt and ERK activation

J Ren, J Duan, KK Hintz, BH Ren - Cardiovascular research, 2003 - academic.oup.com
… ±3 and 138±4 μm in the normal glucose and high glucose groups, respectively (38–40
cells/… electrical stimuli in myocytes from normal glucose and high glucose medium was 5.2±0.5% …

Fueling cardiac hypertrophy

TR Matsuura, TC Leone, DP Kelly - Circulation research, 2020 - Am Heart Assoc
high cardiac FAO rates, are protected against the development of cardiac hypertrophy and
… FAO and increased glucose utilization is required for the cardiac hypertrophic response. …

Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy

Q Wang, Y Sun, T Li, L Liu, Y Zhao… - Molecular …, 2019 - spandidos-publications.com
… that the high expression of BRD4 is involved in the process of cardiac hypertrophy. The aim
… of BRD4 in the process of high glucose (HG)‑induced cardiac hypertrophy, and to clarify …

Metabolic remodeling promotes cardiac hypertrophy by directing glucose to aspartate biosynthesis

J Ritterhoff, S Young, O Villet, D Shao, FC Neto… - Circulation …, 2020 - Am Heart Assoc
… Third, we show that increased glucose utilization in cardiac hypertrophy supports anabolic
metabolism through TCA cycle flux that is antagonized by preserving FAO. As such, our study …

Investigating the mechanism of hyperglycemia-induced fetal cardiac hypertrophy

S Han, G Wang, Y Jin, Z Ma, W Jia, X Wu, X Wang… - PloS one, 2015 - journals.plos.org
cardiac hypertrophy during gestation. However, the mechanism of high-glucose-induced
cardiac hypertrophy … the incidence rate of cardiac hypertrophy dramatically increased in fetuses …

High glucose stimulates aldosterone-induced hypertrophy via type I mineralocorticoid receptors in neonatal rat cardiomyocytes

A Sato, JW Funder - Endocrinology, 1996 - academic.oup.com
… and pathological roles for steroids in terms of cardiac hypertrophy, … their effects under
high glucose conditions. CR activation bv carticosterone, a highly selective type II (glucocorticoid) …