… cell survival and concomitant reduction in apoptosis. We hypothesized that activation of NF-κB
by high glucose … VSMC to examine the effect of age on glucose-related activation of NF-κB…

… cells to high glucose has been shown to cause cell injury, the … proximal tubule epithelial
cells (hPTEC) to high glucose (25 … Acute exposure of hPTEC to high glucose induced a twofold …

… High glucose (HG) induces vascular endothelial cell injury. However, the underlying …
study, we will show that circHIPK3 downregulation by HG mediates endothelial cell injury. …

… showing cell injury with both high glucose and heparinase I treatment suggest that high
glucose may induce heparanase upregulation which degrades HS causing cell injury. This …

… high glucose increases NRK-52E cell … high glucose-induced cell proliferation and oxidative
stress at least in part by increasing AMPK, SIRT1 and Mn-SOD expression in NRK-52E cells. …

… that could protect β cells against chronic hyperglycemia-induced injury has become an …
INS-1 cell injury induced by chronic HG and promote restoration of pancreatic β cells in T2D rats. …

… high glucose-induced cell injury through Wnt/β-catenin signalling pathway in podocytes.
The aim of this study was to investigate effects of D-glucose (30 mm, HG) on podocyte injury …

… Rat renal tubular epithelial cells (NRK-52E cells) were obtained from the American Type
Culture Collection (Rockville, MD, USA). NRK-52E cells were cultured in high glucose DMEM …

… Citation21,Citation22 However, the mechanisms remain unclarified especially concerning
the effect of PI3K/Akt/eNOS signaling on endothelial cell injuries under high serum glucose …

… cells (hRECs) with high glucose (30 mM) for 72 hours. We found that elevated expression of
heparanase by high glucose was … in the presence of high glucose significantly reduced the …