Long‐term results (> 25 years) of a randomized, prospective clinical trial evaluating chemotherapy in patients with highgrade, operable osteosarcoma

NM Bernthal, N Federman, FR Eilber, SD Nelson… - Cancer, 2012 - Wiley Online Library
… In conclusion, the current results suggest that, in patients with high-grade, localized
osteosarcoma who receive neoadjuvant chemotherapy and undergo surgical resection, adjuvant …

[HTML][HTML] Advances in the management of osteosarcoma

SS Bielack, S Hecker-Nolting, C Blattmann… - …, 2016 - ncbi.nlm.nih.gov
… In patients with operable high-grade osteosarcomas, the extent of histological response to
preoperative chemotherapy is a significant predictive factor for both local and systemic control…

… chemotherapy in nonmetastatic patients with highgrade, operable osteosarcomas of the extremities: A report from the Latin A merican Group of Osteosarcoma …

AA Senerchia, CR Macedo, S Ferman, M Scopinaro… - Cancer, 2017 - Wiley Online Library
… The potential effect of MC with continuous oral cyclophosphamide and methotrexate in
patients with highgrade operable osteosarcomas (OSTs) of the extremities was investigated. …

Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group …

SS Bielack, B Kempf-Bielack, G Delling… - Journal of clinical …, 2002 - ascopubs.org
… postoperative chemotherapy with multiple agents as well as surgery of all operable lesions.
high-grade osteosarcoma of bone (1,696 high-grade central and 6 high-grade surface) of an …

Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup

RL Souhami, AW Craft, JW Van der Eijken, M Nooij… - The Lancet, 1997 - thelancet.com
Osteosarcoma Intergroup (EOI) suggested that a short intensive chemotherapy regimen with
doxorubicin and cisplatin might produce survival of operable, non-metastatic osteosarcoma

[HTML][HTML] Survival in high-grade osteosarcoma: improvement over 21 years at a single institution

P Picci, M Mercuri, S Ferrari, M Alberghini, A Briccoli… - Annals of …, 2010 - Elsevier
high-grade osteosarcoma treated at a single institution over a 21-year period (1982–2002)
including all high-grade … clinical trials (primary high-grade osteosarcoma, no evidence of …

Osteosarcoma: improvement in survival limited to high-grade patients only

MU Jawad, MC Cheung, J Clarke, LG Koniaris… - Journal of cancer …, 2011 - Springer
… with osteosarcoma over the past three decades using a population-based registry. … of
osteosarcoma, but the analysis of prognostic factors was limited. Specifically, influence of grade on …

Prognostic factors in high-grade osteosarcoma of theExtremities or trunk: an analysis of 1,702 patients Treatedon Neoadjuvant Cooperative Osteosarcoma Study …

SS Bielack, B Kempf-Bielack, G Delling… - Journal of clinical …, 2023 - ingentaconnect.com
… prognostic factor for patients with localized, operable extremity osteosarcoma."*" Other
variables with possible prognostic impact include tumor size," patient sex” older” or younger age," …

The importance of standardized treatment in high-grade osteosarcoma: 30 years of experience from a hospital-based database

N Aggerholm-Pedersen, K Maretty-Nielsen… - Acta …, 2015 - Taylor & Francis
… Treatment of high-grade osteosarcoma remains a major … survival and prognostic factors of
high-grade osteosarcoma using a recently … in operable osteosarcoma: A study of the European …

Value of P-glycoprotein and clinicopathologic factors as the basis for new treatment strategies in high-grade osteosarcoma of the extremities

M Serra, K Scotlandi, G Reverter-Branchat… - Journal of clinical …, 2003 - ascopubs.org
… curves in 149 patients with high-grade osteosarcoma. (A) … in 149 patients with high-grade
osteosarcoma according to (A) P-… in 40 patients with high-grade osteosarcoma according to P-…