Automated DNA profiling employing multiplex amplification of short tandem repeat loci.
CP Kimpton, P Gill, A Walton, A Urquhart… - Genome …, 1993 - genome.cshlp.org
… STR (or microsatellite) loci consist of simple tandemly repeated sequences of 1-6 bp in …
variable number tandem repeat (VNTR or minisatellite) loci, STRs may exhibit a high degree of …
variable number tandem repeat (VNTR or minisatellite) loci, STRs may exhibit a high degree of …
Genetics and genomics of core short tandem repeat loci used in human identity testing
JM Butler - Journal of forensic sciences, 2006 - Wiley Online Library
… However, it is important to keep in mind that ambiguity is introduced by the relatively high
rate of mutation with STR loci (see Table 6), which makes it challenging to separate alleles that …
rate of mutation with STR loci (see Table 6), which makes it challenging to separate alleles that …
A genomic view of short tandem repeats
M Gymrek - Current opinion in genetics & development, 2017 - Elsevier
… Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
… As a result, STRs exhibit mutation rates that are orders of magnitude higher than other types …
… As a result, STRs exhibit mutation rates that are orders of magnitude higher than other types …
The utility of short tandem repeat loci beyond human identification: implications for development of new DNA typing systems
R Chakraborty, DN Stivers, B Su… - …, 1999 - Wiley Online Library
… Since hypervariability at STR loci is at least partly contributed by their high mutation rate, …
Perhaps, supplementing them with a few additional repeat loci, we will be in a position to …
Perhaps, supplementing them with a few additional repeat loci, we will be in a position to …
A brief review of short tandem repeat mutation
H Fan, JY Chu - Genomics, Proteomics and Bioinformatics, 2007 - academic.oup.com
… Short tandem repeats (STRs) are short tandemly repeated … Because of their polymorphisms
and high mutation rates, STRs … the same mutation rate to that of autosomal loci, suggesting …
and high mutation rates, STRs … the same mutation rate to that of autosomal loci, suggesting …
A polymorphic X-linked tetranucleotide repeat locus displaying a high rate of new mutation: implications for mechanisms of mutation at short tandem repeat loci
MM Mahtani, HF Willard - Human molecular genetics, 1993 - academic.oup.com
… We report a high rate of new mutation at a short tandem repeat sequence polymorphism (STR,
microsatellite) at locus DXS981 on the proximal long arm of the human X chromosome. …
microsatellite) at locus DXS981 on the proximal long arm of the human X chromosome. …
Mutation of human short tandem repeats
JL Weber, C Wong - Human molecular genetics, 1993 - academic.oup.com
… in lymphocytes for other loci (8,17,26). … locus D19S244 in family 1420 is not consistent with
a somatic event. Given the relatively large confidence interval for our estimate of mutation rate…
a somatic event. Given the relatively large confidence interval for our estimate of mutation rate…
Intra‐and inter‐population diversity at short tandem repeat loci in diverse populations of the world
R Deka, MD Shriver, LM Yu, RE Ferrell… - …, 1995 - Wiley Online Library
… may reflect smaller population size and a higher level of isolation. An analysis of genetic …
At a global level, for the six STR loci we observed a total diversity of 76%, of which 1.4% can …
At a global level, for the six STR loci we observed a total diversity of 76%, of which 1.4% can …
[PDF][PDF] CODIS and PCR-based short tandem repeat loci: law enforcement tools
B Budowle, TR Moretti, SJ Niezgoda… - … European symposium on …, 1998 - promega.com
… By taking advantage of the unfortunately high repeat offense rate by some individuals,
combined with the power of forensic DNA technology and utilization of computerized DNA …
combined with the power of forensic DNA technology and utilization of computerized DNA …
Sequencing and characterizing short tandem repeats in the human genome
HA Tanudisastro, IW Deveson, H Dashnow… - Nature Reviews …, 2024 - nature.com
… higher error rates for insertions, whereas ONT generally has higher substitution error rates
and especially high indel … Short tandem repeat (STR) loci are genotyped using whole-genome …
and especially high indel … Short tandem repeat (STR) loci are genotyped using whole-genome …
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