Engineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid
F Cheng, H Yu, G Stephanopoulos - Metabolic engineering, 2019 - Elsevier
… Corynebacterium glutamicum for high-titer HA biosynthesis through systematic design and
metabolic engineering … Enhancement of the HA biosynthesis pathway and attenuation of the …
metabolic engineering … Enhancement of the HA biosynthesis pathway and attenuation of the …
High‐titer biosynthesis of hyaluronic acid by recombinant Corynebacterium glutamicum
F Cheng, Q Gong, H Yu… - Biotechnology …, 2016 - Wiley Online Library
… glutamicum can be particularly expected by fed-batch or continuous cultures. … glutamicum
is selected as a novel recombinant producer to synthesize high titer of HA with satisfying M w …
is selected as a novel recombinant producer to synthesize high titer of HA with satisfying M w …
High-Titer Glutamic Acid Production from Lignocellulose Using an Engineered Corynebacterium glutamicum with Simultaneous Co-utilization of Xylose and Glucose
C Jin, Z Huang, J Bao - … Sustainable Chemistry & Engineering, 2020 - ACS Publications
… of inhibitors and a high conservation of xylose sugar. The major focus of the study is a
stepwise metabolic engineering of C. glutamicum to trigger high-titer glutamate production by …
stepwise metabolic engineering of C. glutamicum to trigger high-titer glutamate production by …
Biosystem design of Corynebacterium glutamicum for bioproduction
… Corynebacterium glutamicum, a natural glutamate-producing … explored recently for high-level
biosynthesis of amino acid … glutamicum isolates and detected GlcNAc titers at 3.0 g/L in …
biosynthesis of amino acid … glutamicum isolates and detected GlcNAc titers at 3.0 g/L in …
Engineering Corynebacterium glutamicum for the de novo biosynthesis of tailored poly-γ-glutamic acid
G Xu, J Zha, H Cheng, MHA Ibrahim, F Yang… - … engineering, 2019 - Elsevier
… Here, we report a metabolically engineered Corynebacterium glutamicum capable of producing
γ-PGA … glutamicum strain that produces γ-PGA in substantially higher titers in variable …
γ-PGA … glutamicum strain that produces γ-PGA in substantially higher titers in variable …
Evolutionary engineering of Corynebacterium glutamicum
RG Stella, J Wiechert, S Noack… - Biotechnology …, 2019 - Wiley Online Library
… higher glutamic acid titer and 35% higher yield than the parental strain. The increased glucose
consumption rate probably resulted from a higher … FACS, or to synthesis of an antibiotic or …
consumption rate probably resulted from a higher … FACS, or to synthesis of an antibiotic or …
Metabolic Engineering of Corynebacterium glutamicum for High‐Level Ectoine Production: Design, Combinatorial Assembly, and Implementation of a …
G Gießelmann, D Dietrich, L Jungmann… - Biotechnology …, 2019 - Wiley Online Library
… high-salt process, which imposes constraints on the costs, design, and durability of the
fermentation system. Here, Corynebacterium glutamicum … discovers several high-titer mutants with …
fermentation system. Here, Corynebacterium glutamicum … discovers several high-titer mutants with …
Synthetic Biology Toolkits and Metabolic Engineering Applied in Corynebacterium glutamicum for Biomanufacturing
M Chai, C Deng, Q Chen, W Lu, Y Liu, J Li… - ACS Synthetic …, 2021 - ACS Publications
… (50) Besides, iCW773 was applied in hyaluronic acid (HA) biosynthesis to predict the …
The GlcNAc titer of the engineering strain increased by 31.9% to 9.1 g/L in a shake flask. (73…
The GlcNAc titer of the engineering strain increased by 31.9% to 9.1 g/L in a shake flask. (73…
Metabolic engineering of Corynebacterium glutamicum for fermentative production of chemicals in biorefinery
… glutamicum strains for platform chemical production, the design of efficient biosynthetic
pathways and the reinforcement of pathways … Recently, higher-titer ethanol production by C. …
pathways and the reinforcement of pathways … Recently, higher-titer ethanol production by C. …
Recent advances in metabolic engineering of Corynebacterium glutamicum for bioproduction of value-added aromatic chemicals and natural products
T Kogure, M Inui - Applied microbiology and biotechnology, 2018 - Springer
… glutamicum can overproduce several commercially valuable … from sugars at remarkably
high titer suitable to commercial … genetic engineering of the carotenoid biosynthesis pathway. …
high titer suitable to commercial … genetic engineering of the carotenoid biosynthesis pathway. …
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