Tissue displacement and impact force are important contributors to outcome after spinal cord contusion injury
… injury, and were capable of controlled hindlimb movement and weight-bearing after 7 days.
All of these animals achieved normal hindlimb … These mice could not walk with full hindlimb …
All of these animals achieved normal hindlimb … These mice could not walk with full hindlimb …
Characterization of spinal cord glial cells in a model of hindlimb unloading in mice
YA Chelyshev, YO Muhamedshina, TV Povysheva… - Neuroscience, 2014 - Elsevier
… Myelinated fibers in the white matter showed prominent myelin destruction. Analysis of the …
Thus, our results showed that hindlimb unloading caused decreases in gray and white matter …
Thus, our results showed that hindlimb unloading caused decreases in gray and white matter …
Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function
DR Reinhardt, KE Stehlik, K Satkunendrarajah… - Experimental …, 2020 - Elsevier
… contusion injury with moderate severity, resulting in an apparent deficit in front and hindlimb
… As expected for a cervical contusion injury, grip strength in the fore limbs was significantly …
… As expected for a cervical contusion injury, grip strength in the fore limbs was significantly …
Experimental hindlimb ischemia increases neutrophil-mediated matrix metalloproteinase activity: a potential mechanism for lung injury after limb ischemia
G Plitas, PJ Gagne, BE Muhs, IA Ianus, JP Shaw… - Journal of the American …, 2003 - Elsevier
… model of hindlimb ischemia (HI) we investigated the role of PMNs in HI-induced changes of
MMP-2 and -9 activities in lung, kidney, and liver tissues. We hypothesize that acute hindlimb …
MMP-2 and -9 activities in lung, kidney, and liver tissues. We hypothesize that acute hindlimb …
Gait analysis in normal and spinal contused mice using the TreadScan system
JE Beare, JR Morehouse, WH DeVries… - Journal of …, 2009 - liebertpub.com
… matter between injury groups, a one-way ANOVA was run on the spared white matter
percentage for each injury … of the hindlimb gait parameters and spared white matter percentage, …
percentage for each injury … of the hindlimb gait parameters and spared white matter percentage, …
A mouse model of graded contusive spinal cord injury
PL KUHN, JR WRATHALL - Journal of neurotrauma, 1998 - liebertpub.com
… In cases where hind limb scores differed in an animal, the less normal score was used for
analysis. All tests were order-balanced between test days. Table 1 provides a description of …
analysis. All tests were order-balanced between test days. Table 1 provides a description of …
Eccentric rehabilitation induces white matter plasticity and sensorimotor recovery in chronic spinal cord injury
Experience-dependent white matter plasticity offers new potential for rehabilitation-induced
recovery after neurotrauma. This first-in-human translational experiment combined myelin …
recovery after neurotrauma. This first-in-human translational experiment combined myelin …
Impact speed does not determine severity of spinal cord injury in mice with fixed impact displacement
… Briefly, two raters blinded to the experimental conditions observed hind limb motor function
of contusion-injured mice from 1 to 21DPI. The rating was done daily during the first week. …
of contusion-injured mice from 1 to 21DPI. The rating was done daily during the first week. …
Spinal cord ischemic injury: Development of a new model in the rat
GK Kanellopoulos, H Kato, CY Hsu, NT Kouchoukos - Stroke, 1997 - Am Heart Assoc
… minutes resulted in permanent hind limb motor deficits in 75… produce rats with significant
hind limb motor function deficits. … , 12 failed to produce hind limb neurological motor deficits in 8 …
hind limb motor function deficits. … , 12 failed to produce hind limb neurological motor deficits in 8 …
Course of motor recovery following ventrolateral spinal cord injury in the rat
AA Webb, GD Muir - Behavioural brain research, 2004 - Elsevier
… hind limb at 2 days and 1.5 weeks after injury compared to before surgery (P<0.05), while right
hind limbs bore more weight compared to the left hind limb at … after spinal cord injury. Fore-…
hind limbs bore more weight compared to the left hind limb at … after spinal cord injury. Fore-…