Mechanobiological predictions of growth front morphology in developmental hip dysplasia

SJ Shefelbine, DR Carter - Journal of Orthopaedic Research, 2004 - Wiley Online Library
… We implemented these mechanobiological principles into a finite element model to predict
… Under loading conditions of the dysplastic hip, the octahedral shear stress was much larger …

[HTML][HTML] Effects of normal and abnormal loading conditions on morphogenesis of the prenatal hip joint: application to hip dysplasia

M Giorgi, A Carriero, SJ Shefelbine, NC Nowlan - Journal of biomechanics, 2015 - Elsevier
… In this study, we develop a mechanobiological simulation of prenatal hip joint … We predict
growth and shape change of an idealised hip joint, correlate our predictions with human hip

Mechanobiological prediction of proximal femoral deformities in children with cerebral palsy

A Carriero, I Jonkers, SJ Shefelbine - Computer methods in …, 2011 - Taylor & Francis
… study, the mechanobiological principles were implemented on a 3D finite element (FE) model
of the proximal femur in order to predict … The FE model predicts an increase in the femoral …

[PDF][PDF] Mechanobiological predictions of fetal joint morphogenesis

M Giorgi - 2015 - core.ac.uk
… the use of a mechanobiological simulation of prenatal joint … time, a 3D mechanobiological
simulation of joint morphogenesis in … time, a mechanobiological simulation of prenatal hip joint …

[HTML][HTML] The role of computational models in mechanobiology of growing bone

E Comellas, SJ Shefelbine - Frontiers in bioengineering and …, 2022 - frontiersin.org
… Computer models specifically allow us to digitally reproduce structures or systems that we
can use to probe influences and predict consequences. Computational mechanics models, …

[HTML][HTML] Finite element analysis of mechanical behavior of human dysplastic hip joints: a systematic review

B Vafaeian, D Zonoobi, M Mabee… - Osteoarthritis and …, 2017 - Elsevier
… of DDH through simulating mechanobiological growth of … to reliable quantitative prediction
of hip mechanical behavior. In … associated with hip dysplasia occurred in the hip models with …

[HTML][HTML] Mechanobiological simulations of prenatal joint morphogenesis

M Giorgi, A Carriero, SJ Shefelbine, NC Nowlan - Journal of biomechanics, 2014 - Elsevier
… This study predicts joint shape morphogenesis in 3D using a novel mechanobiology
theory for cartilage growth. Our simulations predict a range of anatomically recognisable joint …

Pathobiological Analysis of Developmental Dysplasia of the Hip and Its Progression to Osteoarthritis

P Wolfe - 2022 - search.proquest.com
… investigated molecular biology, mechanobiology, biomechanics, … predicting hip status as
dysplastic or healthy at 2 years of age.Based on the similarities between canine hip dysplasia

In silico bone mechanobiology: modeling a multifaceted biological system

M Giorgi, SW Verbruggen… - … Reviews: Systems Biology …, 2016 - Wiley Online Library
… for predicting mechanobiological changes to bone tissue and (2) models investigating cell
mechanobiology. … to shed further light on bone mechanobiology. Finally, although the ever-…

Neonatal Hip Loading in Developmental Dysplasia: Finite Element Simulation of Proximal Femur Growth and Treatment

SM Sadeghian, OJ Arthurs, X Li, CL Lewis… - HSS Journal …, 2023 - journals.sagepub.com
… are critical to prevent acetabular dysplasia and proximal femoral … with mechanobiological
principles. We explore the effects of … in a Pavlik harness on predicted proximal femur growth. …