过去一年中添加的文章,按日期排序

WTAP-mediated m6A methylation of PHF19 facilitates cell cycle progression by remodeling the accessible chromatin landscape in t (8; 21) AML

XN Gao, YQ Li, D Liu, L Wang, YL Shao, HS Zhou… - 2024 - researchsquare.com
80 天前 - … is that unlike genetic changes such as chromosomal rearrangements and gene
mutations, epigenetic changes are reversible. Therefore, epigenetic regulators represent a …

[HTML][HTML] METTL Family in Healthy and Disease

J He, F Hao, S Song, J Zhang, H Zhou, J Zhang… - Molecular Biomedicine, 2024 - Springer
80 天前 - Histone modifications regulate the extent of chromatin relaxation, affecting the
binding of transcription factors and promoting transcriptional activity of RNA polymerase. …

[HTML][HTML] AB002. DNA methylation-regulated genes contribute to temozolomide (TMZ) resistance by scaffolding paraspeckle proteins

J Cai - Chinese Clinical Oncology, 2024 - cco.amegroups.org
83 天前 - … shows that epigenetic modifications including DNA methylation and … DNA
methyltransferase 1 (DNMT1) and the recruitment of DNMT1 at the HSD52 promoter to attenuate …

[HTML][HTML] Epigenetics and Control of Tumor Angiogenesis in Melanoma: An Update with Therapeutic Implications

G Cazzato, N Sgarro, N Casatta, C Lupo, G Ingravallo… - Cancers, 2024 - mdpi.com
85 天前 - … potential of targeting epigenetic modifications to inhibit angiogenesis in melanoma.
Epigenetic drugs, such as DNA methyltransferase inhibitors (eg, 5-azacytidine) and …

[HTML][HTML] Glyphosate and a glyphosate-based herbicide dysregulate the epigenetic landscape of Homeobox A10 (Hoxa10) gene during the endometrial receptivity in …

J Varayoud, MM Milesi, DB Cadaviz, F Doná… - Frontiers in …, 2024 - frontiersin.org
91 天前 - … plus lactational phases induces epigenetic modifications in regulatory regions of
uterine … a GBH cause comparable gene expression and epigenetic changes. Our results might …

Improving Gastric Motility in Aging through EZH2 Inhibition and Preservation of Interstitial Cells of Cajal

S Ro - Cellular and Molecular Gastroenterology and …, 2024 - cmghjournal.org
91 天前 - … One of the most conserved indicators of aging is the alteration in epigenetic
markers, such as histone modifications and DNA methylation,10 which may contribute to the …

The PVT1, HULC, and HOTTIP expression changes due to treatment in Diffuse Large B-cell lymphoma

M Shahsavari, S Arbabian, F Hosseini, MR Razavi - bioRxiv, 2024 - biorxiv.org
92 天前 - … with histone 88 modification, DNA methylation/demethylation, and protein
methyltransferase … Long noncoding 587 RNA as modular scaffold of histone modification

GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis

K Guo, Y Cao, Z Zhao, J Zhao, L Liu, H Wang - Epigenetics, 2024 - Taylor & Francis
92 天前 - … During spermiogenesis, extensive histone modifications have been reported to occur
histone-modifying enzymes or histone modification in the reaction. Histone modifications

H3K14ac facilitates the reinstallation of constitutive heterochromatin in Drosophila early embryos by engaging Eggless/SetDB1

R Tang, M Zhou, Y Chen, Z Jiang, X Fan… - Proceedings of the …, 2024 - pnas.org
93 天前 - … of the H3K9 methyltransferase Eggless/SetDB1 (7). Our study reports a mode of
recruitment of Eggless/SetDB1, in which an active histone modification H3K14ac directly …

[HTML][HTML] A comprehensive study on epigenetic signatures to monitor disease progression and the response to therapy in breast cancer

D Parikh, M Shah - Biomedical Analysis, 2024 - Elsevier
93 天前 - … by current epigenetic therapies, such as DNA methyltransferase inhibitors and
histone … highlights the crucial role of DNA methylation patterns, histone modifications, and non-…