Histopathologic analysis of suspected amiodarone hepatotoxicity

JH Lewis, F Mullick, KG Ishak, RC Ranard, B Ragsdale… - Human pathology, 1990 - Elsevier
This analysis of the morphology of suspected amiodarone (AD) liver disease is based on a
study of liver specimens from 17 individuals. Changes similar to alcoholic liver injury were …

Amiodarone hepatotoxicity

M Babatin, SS Lee, PT Pollak - Current vascular pharmacology, 2008 - ingentaconnect.com
… The predominant histological lesions observed in amiodarone-induced liver injury … histology
of liver lesions resembles that of alcoholic hepatitis, but even patients receiving amiodarone

[HTML][HTML] Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports

T Tsuda, H Tada, Y Tanaka, N Nishida… - Journal of medical case …, 2018 - Springer
… We report the clinical and histological features of two contrasting Japanese patients with …
Histological features of amiodarone-induced hepatotoxicity are similar to alcoholic hepatitis and …

Granular cells as a marker of early amiodarone hepatotoxicity: a pathological and analytical study.

NA Shepherd, AM Dawson, PR Crocker… - Journal of clinical …, 1987 - jcp.bmj.com
… We report two cases of amiodarone hepatotoxicity. We believe that the histological features
… of the earliest morphological changes of amiodarone hepatotoxicity and that those of the …

Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients

JH Lewis, RC Ranard, A Caruso, LK Jackson… - Hepatology, 1989 - journals.lww.com
… The histopathologic features of our nine cases included Mallory bodies in five (zone 1 in
three), steatosis in eight, foam cells in four and acidophilic bodies or degeneration in nine. Mild …

Amiodarone hepatotoxicity: a clinicopathologic study of five patients

B RIGAS, LE ROSENFELD, KW BARWICK… - Annals of Internal …, 1986 - acpjournals.org
… Five patients had amiodarone hepatotoxicity detected on routine biochemical monitoring. …
We report the clinical and histologic features of five patients with amiodarone hepatotoxicity. …

Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use

K Raja, SN Thung, MI Fiel… - Seminars in Liver Disease, 2009 - thieme-connect.com
… and its effects on the liver was in the 1980s and 1990s when our concepts of nonalcoholic
fatty liver disease and its histological resemblance to alcoholic hepatitis were developing. …

Hepatotoxicity during rapid intravenous loading with amiodarone: description of three cases and review of the literature

AER Bravo, J Drewe, RG Schlienger… - Critical care …, 2005 - journals.lww.com
Amiodarone can effectively prevent and … amiodarone, which can be fatal, is not well
recognized. We describe three cases of acute hepatocellular injury after intravenous amiodarone

[HTML][HTML] The protective effect of grape seed and Ginkgo biloba against hepatotoxicity induced by the antidysrhythmic drug “amiodarone” in male albino rats

M Abdul-Hamid, SR Galaly, H Mahmoud… - Beni-suef university …, 2018 - Elsevier
… The aim of this study was to evaluate the possible protective effect of grape seed and
Ginkgo biloba against the hepatotoxicity induced by amiodarone through histological, …

[HTML][HTML] Autophagy alleviates amiodarone-induced hepatotoxicity

F Wandrer, Ž Frangež, S Liebig, K John, F Vondran… - Archives of …, 2020 - Springer
… we analyzed the mechanisms of amiodarone-mediated liver injury. We found that amiodarone-…
-18 compared to healthy individuals or patients not receiving amiodarone. Furthermore, …