HIV-1 antiretroviral drug therapy

EJ Arts, DJ Hazuda - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
… Combination antiretroviral therapy dramatically suppresses viral replication and reduces the
plasma HIV-1 viral load (vLoad) to below the limits of detection of the most sensitive clinical …

[HTML][HTML] Antiretroviral therapy for the prevention of HIV-1 transmission

MS Cohen, YQ Chen, M McCauley… - … England Journal of …, 2016 - Mass Medical Soc
… ) 052 trial showed that antiretroviral therapy (ART) prevented … by human immunodeficiency
virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1

Immunological recovery and antiretroviral therapy in HIV-1 infection

M Battegay, R Nüesch, B Hirschel… - The Lancet infectious …, 2006 - thelancet.com
HIV-1 RNA is durably suppressed by antiretroviral therapy, in patients with incomplete
suppression of plasma HIV-1 … to weeks after the start of antiretroviral therapy, is briefly described. …

The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic

S Broder - Antiviral research, 2010 - Elsevier
antiretroviral therapies both in our lab and clinic. In 1985–1986, we helped define an orally
therapeutic range for AZT, thereby providing the first proof that effective inhibition of HIV-1

Prevention of HIV-1 infection with early antiretroviral therapy

MS Cohen, YQ Chen, M McCauley… - New England journal …, 2011 - Mass Medical Soc
… of antiretroviral therapy reliably prevents HIV-1 transmission … early antiretroviral therapy had
a clinical benefit for both HIV-1… These results support the use of antiretroviral treatment as a …

[HTML][HTML] A quantitative basis for antiretroviral therapy for HIV-1 infection

BL Jilek, M Zarr, ME Sampah, SA Rabi, CK Bullen… - Nature medicine, 2012 - nature.com
Highly active antiretroviral therapy (HAART) 1 , 2 , 3 has dramatically decreased mortality
from HIV-1 infection 4 and is a major achievement of modern medicine. However, there is no …

HIV-1 antiretroviral resistance: scientific principles and clinical applications

MW Tang, RW Shafer - Drugs, 2012 - Springer
… the emergence of HIV-1 drug resistance was central to the development of successful ARV
therapy (ART). Nonetheless, the acquisition and transmission of HIV-1 drug resistance loom …

Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy

T Le, EJ Wright, DM Smith, W He… - … England Journal of …, 2013 - Mass Medical Soc
Human immunodeficiency virus type 1 (HIV-1) infection is characterized by a … antiretroviral
therapy (ART). To test this hypothesis, we evaluated a large, well-characterized cohort of HIV-1

Timing of antiretroviral therapy for HIV-1 infection and tuberculosis

DV Havlir, MA Kendall, P Ive… - … England Journal of …, 2011 - Mass Medical Soc
Antiretroviral therapy (ART) is indicated during tuberculosis treatment in patients infected
with human immunodeficiency virus type 1 (HIV-1), but the timing for the initiation of ART when …

Forgiveness of non-adherence to HIV-1 antiretroviral therapy

J Shuter - Journal of Antimicrobial Chemotherapy, 2008 - academic.oup.com
… Superior adherence to HIV-1 antiretroviral therapy is a mainstay of successful HIV management.
Studies performed in the early era of highly active antiretroviral therapy demonstrated …