… perturbation of CD4+ cell function and maintenance of HIV infection; most such changes
involve … of both expression and function of the CD4 molecule. RETROVIRAL RECEPTORS …

… Given this functional convergence, it is believed that cell surface CD4 … CD4 receptor by
HIV-1 and describes our current comprehension of the role of CD4 down-regulation during HIV-1 …

… It interacts with the primary receptor CD4 and coreceptor (eg, chemokine receptor … of HIV-1
Env and its complexes with the cellular receptors have revealed molecular details of HIV-1 …

… interactions of the HIV-1 envelope protein to cellular CD4 receptors. Further confirmation …
the HIV-1 envelope. In particular, two substitutions, M426L and M475I, are situated in the CD4 …

… In summary, we show that mAb 2D5 binds with high affinity to the CD4 receptor and blocks
HIV-1 entry in vitro but lacks robust in vivo protective efficacy despite high plasma levels. In …

… To gain further insight into how the gp120–CD4 complex interacts with CCR-5 on
activated CD4" T cells, we used a panel of HIV-1 neutralizing and non-neutralizing anti-gp120 …

… receptors can be used as co-receptors for HIV-1 variants". The regions of gp120 and CD4
… CD4. This implies that significant conformational rearrangements of envelope glycoprotein–…

… CD4 receptor by the human immunodeficiency virus type 1 gpl20 exterior envelope glycoprotein
is important for virus entry and cytopathic effect. To investigate the CD4… the CD4 receptor…

… CD4 receptor during viral infection. In the present study, we have investigated the role of CD4
down-modulation in the HIV-1 … Vpu-mediated CD4 degradation modulates positively HIV-1 …

… HIV virus particles interact with several receptors on cell surfaces. Two receptors, CD4
and a co-receptor act … For HIV-1, the chemokine receptor CCR5 is the predominant co-…