The significance of interferon-γ in HIV-1 pathogenesis, therapy, and prophylaxis
SR Roff, EN Noon-Song, JK Yamamoto - Frontiers in immunology, 2014 - frontiersin.org
… of IFNγ in HIV-1 therapy. Concomitantly, a number of in vitro studies tested the anti-HIV activity
of IFNγ on HIV-1 … investigated whether IFNγ has therapeutic effects against HIV-1 in HIV + …
of IFNγ on HIV-1 … investigated whether IFNγ has therapeutic effects against HIV-1 in HIV + …
Vδ1 T lymphocytes producing IFN-γ and IL-17 are expanded in HIV-1–infected patients and respond to Candida albicans
…, A Ferrera, M Setti, G Murdaca… - Blood, The Journal …, 2009 - ashpublications.org
… In early HIV-1 infection, Vδ1 T lymphocytes are increased in peripheral blood and this is …
, in HIV-1–infected patients ex vivo–isolated Vδ1 T cells display cytoplasmic interferon-γ (IFN-γ). …
, in HIV-1–infected patients ex vivo–isolated Vδ1 T cells display cytoplasmic interferon-γ (IFN-γ). …
… human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-γ) promoter and subsequent …
JA Mikovits, HA Young, P Vertino, JPJ Issa… - … and cellular biology, 1998 - Am Soc Microbiol
… IFN-γ gene as a candidate. We show here that acute infection of cells with human
immunodeficiency virus type 1 (HIV-1… of a CpG dinucleotide in the IFN-γ gene promoter, resulting …
immunodeficiency virus type 1 (HIV-1… of a CpG dinucleotide in the IFN-γ gene promoter, resulting …
Sustained high levels of serum interferon-γ during HIV-1 infection: a specific trend different from other cytokines
…, T Uehira, H Yonemoto, H Bando, Y Ogawa… - Viral …, 2010 - liebertpub.com
… characteristic increases in IFN-γ levels due to HIV-1 infection. ART has been … HIV-1 infection
(16,22,23,25), and increases the levels of IL-21, which are reduced in patients with HIV-1 …
(16,22,23,25), and increases the levels of IL-21, which are reduced in patients with HIV-1 …
Cytokines and HIV-1: interactions and clinical implications
K Kedzierska, SM Crowe - antiviral Chemistry and …, 2001 - journals.sagepub.com
… HIV-1 infection secretion of T-helper type 1 (Th1) cytokines, such as interleukin (IL)-2, and
antiviral interferon (IFN)-γ… , IL-4, IL-10, proinflammatory cytokines (IL-1, IL-6, IL-8) and tumour …
antiviral interferon (IFN)-γ… , IL-4, IL-10, proinflammatory cytokines (IL-1, IL-6, IL-8) and tumour …
HIV-1 and interferons: who's interfering with whom?
T Doyle, C Goujon, MH Malim - Nature Reviews Microbiology, 2015 - nature.com
… of interferons (IFNs) to inhibit HIV-1 replication in cell culture models has long been recognized,
and the therapeutic administration of IFNα to HIV-1-… Conversely, studies of chronic HIV-1 …
and the therapeutic administration of IFNα to HIV-1-… Conversely, studies of chronic HIV-1 …
HIV-1-specific IFN-γ/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells
…, F Vallelian, PA Bart, G Pantaleo - Proceedings of the …, 2005 - National Acad Sciences
… for the combined loss of HIV-1-specific IFN-γ/IL-2-secreting and -proliferating CD8 T cells
in progressive HIV-1 infection. This association raised the issue on the role of IFN-γ/IL-2-…
in progressive HIV-1 infection. This association raised the issue on the role of IFN-γ/IL-2-…
Increased IFN-γ production by NK and CD3+/CD56+ cells in sexually HIV-1-exposed but uninfected individuals
… The anti-viral effects of IFN-γ are well established, and so our results suggest that IFN-γ …
factors involved in controlling the establishment of sexually transmitted HIV-1 infection. …
factors involved in controlling the establishment of sexually transmitted HIV-1 infection. …
Presence of HIV-1 Gag-specific IFN-γ+ IL-2+ and CD28+ IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection
MJ Boaz, A Waters, S Murad… - The Journal of …, 2002 - journals.aai.org
… combined expression of IFN-γ and IL-2 as well as CD28, rather than production of IFN-γ
alone, by HIV-specific CD4 T cells is important in nonprogression following HIV-1 infection. In …
alone, by HIV-specific CD4 T cells is important in nonprogression following HIV-1 infection. In …
IL-13 and IFN-γ secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression
RT Bailer, A Holloway, J Sun, JB Margolick… - The Journal of …, 1999 - journals.aai.org
… In this report, IL-13 and IFN-γ were analyzed in progressive HIV-1 disease. Both cytokines
… and inhibit HIV-1 infection of macrophages. Anti-CD3/anti-CD28-activated PBMC from HIV-1-…
… and inhibit HIV-1 infection of macrophages. Anti-CD3/anti-CD28-activated PBMC from HIV-1-…
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