The macrophage in HIV-1 infection: from activation to deactivation?

G Herbein, A Varin - Retrovirology, 2010 - Springer
… Since the capacity of macrophages to support productive HIV-1 infection is known to be … of
macrophage activation by cytokines impacts the capacity to support productive HIV-1 infection. …

Macrophage polarization and HIV-1 infection

E Cassol, L Cassetta, M Alfano… - Journal of leukocyte …, 2010 - academic.oup.com
… modulation of macrophage activation in persons coinfected with HIV-1. As with most microbes,
acute Mtb infection drives these cells toward an M1 phenotype [148, 149]. Experimentally…

Macrophage signaling in HIV-1 infection

G Herbein, G Gras, KA Khan, W Abbas - Retrovirology, 2010 - Springer
… exogenous HIV-1 proteins are able to enter macrophages and … involved in the activation of
macrophages in HIV infection is … Macrophage activation and production of pro-inflammatory …

Mechanisms for macrophage-mediated HIV-1 induction

K Devadas, NJ Hardegen, LM Wahl… - The Journal of …, 2004 - journals.aai.org
activation of HIV-1 replication in latently infected U1 or ACH2 cells by human macrophages
is … Multiplexed RT-PCR amplification of mRNA isolated from cocultures of macrophages and …

Biomarkers of microbial translocation and macrophage activation: association with progression of subclinical atherosclerosis in HIV-1 infection

T Kelesidis, MA Kendall, OO Yang… - The Journal of …, 2012 - academic.oup.com
macrophage activation, respectively, but have not been previously studied in of the context
of atherosclerosis in HIV … between HIV-infected individuals receiving PI-based treatment, HIV-…

Microbial translocation induces persistent macrophage activation unrelated to HIV-1 levels or T-cell activation following therapy

MA Wallet, CA Rodriguez, L Yin, S Saporta… - Aids, 2010 - journals.lww.com
HIV-1 replication and microbial translocation occur concomitant with … activation. This
study delineates mechanisms of immune activation and CD4 T-cell decline in pediatric HIV-1

Macrophages and HIV-1: dangerous liaisons

A Verani, G Gras, G Pancino - Molecular immunology, 2005 - Elsevier
… Among the viral proteins implicated in macrophage activation, Nef appears to play a
prominent role. Nef is a 27-kDa protein that is produced early during infection and exerts multiple …

The neuropathogenesis of HIV-1 infection

HE Gendelman, SA Lipton, M Tardieu… - Journal of Leucocyte …, 1994 - academic.oup.com
… /or cellular products produced from HIV-1-infected macrophages injure neurons and induce
… produced from HIV-infected macrophages are central to uncovering how HIV mediates CNS …

The role of macrophages in HIV-1 persistence and pathogenesis

Z Kruize, NA Kootstra - Frontiers in microbiology, 2019 - frontiersin.org
… An advantage of this in vitro culture system is that large number of cells are available for
analysis and macrophage activation, differentiation, polarization and function can easily be …

CNS inflammation and macrophage/microglial biology associated with HIV-1 infection

A Yadav, RG Collman - Journal of neuroimmune pharmacology, 2009 - Springer
… findings that support the critical role and mechanisms of monocyte/macrophage activation
and inflammation as a major component for HIV-1 encephalitis or HIV-1 associated dementia. …