Immune activation and HIV persistence: implications for curative approaches to HIV infection

NR Klatt, N Chomont, DC Douek… - Immunological …, 2013 - Wiley Online Library
… is known about immune activation and HIV persistence during … immune system interact
once treatment-mediated control of … immune activation might contribute to HIV persistence, HIV

Immune activation and inflammation in HIV‐1 infection: causes and consequences

V Appay, D Sauce - The Journal of Pathology: A Journal of the …, 2008 - Wiley Online Library
Immune activation in HIV infection is a rather broad expression that covers a large range
of events or observations involved in active molecular and cellular processes (eg related to …

[HTML][HTML] Immune activation in the context of HIV infection

Z Bentwich, A Kalinkovich, Z Weisman… - Clinical and …, 1998 - ncbi.nlm.nih.gov
immune activation by infectious agents to render infected people's cells more susceptible
to HIV infection … of conventionally activated cells, we would also expect chronic activation to …

HIV‐associated chronic immune activation

M Paiardini, M Müller‐Trutwin - Immunological reviews, 2013 - Wiley Online Library
… There are multiple molecular and cellular mechanisms by which HIV infection could
induce generalized immune activation. Among these, as summarized in this cartoon, …

HIV as a cause of immune activation and immunosenescence

T Sokoya, HC Steel, M Nieuwoudt… - Mediators of …, 2017 - Wiley Online Library
… IFNs I and II are produced by the innate immune system during HIV infection. IFN I plays an
important role in mediating continuous inflammation. It is produced by plasmacytoid dendritic …

Inflammation, immune activation, and antiretroviral therapy in HIV

CO Hileman, NT Funderburg - Current Hiv/aids reports, 2017 - Springer
… the heightened immune activation present with HIV infection, especially … immune activation
in HIV-infected persons on ART is likely the result of several mechanisms. First, persistent HIV

Immune activation and AIDS pathogenesis

DL Sodora, G Silvestri - Aids, 2008 - journals.lww.com
… – is needed to ascertain and better characterize the pathogenic role of immune activation
during HIV infection. Ideally, the best type of ‘experiment’ would involve treatment of SIV-…

Immune activation in HIV-infected African individuals

G Rizzardini, D Trabattoni, M Saresella, S Piconi… - Aids, 1998 - journals.lww.com
immune activation accompanies HIV infection in Africa and is present even in Ugandan HIV-…
by PBMC of HIV-infected Ugandan patients; (2) IFN-γ and IL-10 production is augmented in …

Immune activation and HIV: an enduring relationship

I Sereti, M Altfeld - Current Opinion in HIV and AIDS, 2016 - journals.lww.com
… Opinion in HIV and AIDS, an overview of the topic of immune activation in HIV is presented
… The association of residual immune activation with clinical outcomes has long been noted …

Chronic innate immune activation as a cause of HIV-1 immunopathogenesis

A Boasso, GM Shearer - Clinical immunology, 2008 - Elsevier
… the chronic immune activation hypothesis, in which HIV infection primarily induces chronic …
associated with innate immunity. Thus, we view chronic innate immune activation to be mainly …