Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection

PW Hunt, E Sinclair, B Rodriguez… - … Journal of infectious …, 2014 - academic.oup.com
… and immune activation [21, 22]. While this pathway predicted mortality in a cohort of HIV-infected
HIV infection in resource-rich settings remains unclear. It is also unclear whether T-cell …

[HTML][HTML] The role of platelet-activating factor in chronic inflammation, immune activation, and comorbidities associated with HIV infection

T Kelesidis, V Papakonstantinou, P Detopoulou… - AIDS …, 2015 - ncbi.nlm.nih.gov
… However, the relative contributions of viremia, immune activation, … immune activation is a
hallmark of HIV-1 pathogenesis; thus the chronic inflammation associated with HIV-1 infection

Persistent immune activation in HIV-1 infection is associated with progression to AIDS

MD Hazenberg, SA Otto, BHB van Benthem, MTL Roos… - Aids, 2003 - journals.lww.com
… of the immune system. In fact, elevated immune activation is related to the outcome of HIV-1
infection… Using proportional hazards models, various parameters for immune activation have …

An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection

JJ Sevigny, SM Albert, MP McDermott… - Archives of …, 2007 - jamanetwork.com
immune activation marker, independently predicts disease progression in advanced HIV-1
infection. … Background Several markers of immune activation have been identified as potential …

[HTML][HTML] Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

A Schuetz, C Deleage, I Sereti, R Rerknimitr… - PLoS …, 2014 - journals.plos.org
… two signature events in HIV infection, CD4 T-cell depletion and chronic inflammation, which
might explain the high levels of local and systemic immune activation observed in this study. …

Reduction of immune activation with chloroquine therapy during chronic HIV infection

SM Murray, CM Down, DR Boulware… - Journal of …, 2010 - Am Soc Microbiol
HIV infection-induced T-cell immune activation (14). Here, we report results using samples
from a clinical study of HIV-infected … of immune activation during the course of CQ treatment. …

[PDF][PDF] P-Selectin and Immune Activation in HIV: Clinical Implications

EI Obeagu, GU Obeagu - Elite Journal of Health Science, 2024 - academia.edu
… in immune activation and inflammation. In the context of human immunodeficiency virus (HIV)
infection… risk, thereby contributing to the multifaceted clinical manifestations of HIV infection.…

Association between immune activation, changes of iron metabolism and anaemia in patients with HIV infection

D Fuchs, R Zangerle, E Artner‐Dworzak… - European journal of …, 1993 - Wiley Online Library
… We conclude that low haemoglobin levels in patients with HIV infection is at least partly
due to immune activation phenomena. Endogenous release of cytokines such as IFN-y by …

[HTML][HTML] Immune activation response in chronic HIV-infected patients: influence of Hepatitis C virus coinfection

M Marquez, P Romero-Cores, M Montes-Oca… - PLoS …, 2015 - journals.plos.org
… phase of immune reconstitution and control of HIV viremia, … HIV infection with a time of
infection of more than 20 years, such as those studied in the present work, the immune activation

Chronic immune activation associated with chronic helminthic and human immunodeficiency virus infections: role of hyporesponsiveness and anergy

G Borkow, Z Bentwich - Clinical Microbiology Reviews, 2004 - Am Soc Microbiol
… , there are several common features to HIV infection and chronic helminthic infections which
we think are due to the fact that both are situations of chronic immune activation. There are, …