HIV infection, immunodeficiency, viral replication, and the risk of cancer

MJ Silverberg, C Chao, WA Leyden, L Xu… - … Biomarkers & Prevention, 2011 - AACR
… The index date for HIV-infectedHIV infected, and in HIV care, defined as the first recorded
CD4 cell count measurement in the health system. Health plan members without HIV infection

HIV-1 replication

EO Freed - Somatic cell and molecular genetics, 2001 - Springer
HIV replication proceeds in a series of events … replication cycle can be viewed most simply
as proceeding in an ordered, step-wise manner. In this chapter, each step in virus replication

CD8+ Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication

CM Walker, DJ Moody, DP Stites, JA Levy - Science, 1986 - science.org
virus replication. However, after reconstitution with only 0.375 x 106 CD8+ cells, HIV could be
… CD8+ lymphocytes suppressed virus replication by a nonspecific "overcrowding" effect, we …

… as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease

MS Meltzer, M Nakamura, BD Hansen… - AIDS research and …, 1990 - liebertpub.com
… In contrast, virus isolation from blood leukocytes of HIVinfected patients onto the same M-CSF-…
Virus isolation from blood of infected individuals was independentof the subject's age, sex, …

Multiple modes of cellular activation and virus transmission in HIV infection: a role for chronically and latently infected cells in sustaining viral replication

Z Grossman, MB Feinberg… - Proceedings of the …, 1998 - National Acad Sciences
… We discuss models of HIV infection that implicitly assume nominally efficient LRT to be the
only relevant mode of transmission. We indicate the limited compliance of these models with …

HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis

KC Williams, TH Burdo - Apmis, 2009 - Wiley Online Library
… macaques, such as Mamu-A * 01-, Mamu-B * 17-, and Mamu-B * 08-positive animals, that
control viral replication will be a useful tool to understand how humans control HIV infection. …

HIV controllers: a homogeneous group of HIV-1—infected patients with spontaneous control of viral replication

O Lambotte, F Boufassa, Y Madec… - Clinical Infectious …, 2005 - academic.oup.com
… All patients had stage A HIV infection, according to the Centers for Disease Control and …
The main characteristic common to these patients was the control of HIV replication. The HIV

Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis

PY Hsue, PW Hunt, A Schnell, SC Kalapus, R Hoh… - Aids, 2009 - journals.lww.com
… Consistent with this theory, untreated HIV infection has been associated with increased …
and treated HIV infection [9] . Considered together, these observations suggest that HIV disease …

Metabolic abnormalities and viral replication are associated with biomarkers of vascular dysfunction in HIVinfected children

…, Pediatric HIV/AIDS Cohort Study (PHACS) - HIV …, 2012 - Wiley Online Library
HIV-infected … to HIV infection in adults will be observed as HIV-infected children age.
Emerging evidence from large, long-term and prospective studies on CVD risk in non-HIV-infected

HIV infection

SG Deeks, J Overbaugh, A Phillips… - Nature reviews Disease …, 2015 - nature.com
… the order of one mutation every few replication events 26 . This high error rate coupled with
continual high-level virus replication leads to the extensive variation in HIV-1. Which of these …