Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1 …

RI Connor, H Mohri, Y Cao, DD Ho - Journal of virology, 1993 - Am Soc Microbiol
… infected with human immunodeficiency virus type 1 (HIV-1). Changes in viral burden which
… longitudinal study of the temporal relationship between viral burden, CD4+ T-cell numbers, …

Brain viral burden in HIV infection

CL Achim, R Wang, DK Miners… - … of neuropathology and …, 1994 - academic.oup.com
… ) to detect HIV gp41 (9), we developed a semiquantitative scale to assess viral burden within
the brains … Based upon the abundance of viral envelope protein detected, we found that HIV

Use of the community viral load as a population-based biomarker of HIV burden

AD Castel, M Befus, S Willis, A Griffin, T West, S Hader… - Aids, 2012 - journals.lww.com
… population's viral burden, and are useful in assessing trends in local HIV/AIDS epidemics.
Measurement of CVL is a novel tool for assessing the potential impact of population-level HIV

Cell-associated viral burden provides evidence of ongoing viral replication in aviremic HIV-2-infected patients

RS Soares, R Tendeiro, RB Foxall, AP Baptista… - Journal of …, 2011 - Am Soc Microbiol
viral replication in HIV-2 + patients, further emphasizing the dichotomy between amount of
plasma virus and cell-associated viral burden … of therapeutic guidelines for HIV-2 infection. …

Relationship between CD4 count, viral burden, and quality of life over time in HIV-1-infected patients

KP Weinfurt, RJ Willke, HA Glick, WW Freimuth… - Medical care, 2000 - journals.lww.com
… as CD4 counts and viral burden (HIV-1 RNA) … viral burden (RNA copies/mL) are related to
changes in HRQOL as indexed by the Medical Outcomes Study HIV Health Survey (MOS-HIV

Viral load and heterosexual transmission of human immunodeficiency virus type 1

TC Quinn, MJ Wawer, N Sewankambo… - New England journal …, 2000 - Mass Medical Soc
… of human immunodeficiency virus type 1 (HIV-1). In a … was HIV-1–positive and one was
initially HIV-1–negative and followed them prospectively for up to 30 months. The incidence of HIV

Copy-years viremia as a measure of cumulative human immunodeficiency virus viral burden

SR Cole, S Napravnik, MJ Mugavero… - American journal of …, 2010 - academic.oup.com
… Plasma human immunodeficiency virus type 1 (HIV-1) viral load is a valuable tool for HIV
research and clinical care but is often used in a noncumulative manner. The authors developed …

High viral burden in the presence of major HIV‐specific CD8+ T cell expansions: evidence for impaired CTL effector function

S Kostense, GS Ogg, EH Manting… - European journal of …, 2001 - Wiley Online Library
… T cell antigen responsiveness to HIV peptide stimulation in vitro… that most HIV-infected patients
have sustained HIV-specific T … virus-specific CD8 + T cells in the face of high viral burden. …

Viral load and disease progression in infants infected with human immunodeficiency virus type 1

WT Shearer, TC Quinn, P LaRussa… - … England Journal of …, 1997 - Mass Medical Soc
… The average viral burden and the slope of the decline in the viral burden between months
1 and 12 were calculated from all available values during this period, among infants with at …

Impact of HIV type 1 subtype variation on viral RNA quantitation

B Parekh, S Phillips, TC Granade, J Baggs… - AIDS research and …, 1999 - liebertpub.com
… However the missed specimens had viral burden near the lower limit (1000 copies/ml) for
these assays. For the 20 subtype E specimens, MONITOR-1.0 and NASBA quantified RNA in …