Identification of HLA-A2-or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma

H Komori, T Nakatsura, S Senju, Y Yoshitake… - Clinical Cancer …, 2006 - AACR
tumor expressing mouse GPC3 both in vitro and in vivo (10). Because the structural motifs
of peptides bound to HLA-A24 (A*… as a cancer immunotherapy modality for HLA-A24 + HCC …

Identification of an HLAA*24:02‐restricted α‐fetoprotein signal peptide‐derived antigen and its specific T‐cell receptor for T‐cell immunotherapy

Z Li, H Gong, Q Liu, W Wu, J Cheng, Y Mei… - …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common type of liver cancer with limited … )
-engineered T-cell immunotherapies specific for human leukocyte antigen (HLA) -A*02:01-…

Identification of α‐fetoprotein‐derived peptides recognized by cytotoxic T lymphocytes in HLA‐A24+ patients with hepatocellular carcinoma

E Mizukoshi, Y Nakamoto, H Tsuji… - … journal of cancer, 2006 - Wiley Online Library
… In our study, we examined 38 HLA-A24 positive patients with HCC who were admitted to
Kanazawa University Hospital between January 2002 and August 2003, consisting of 30 men …

Usefulness of a novel oncofetal antigen, glypican-3, for diagnosis and immunotherapy of hepatocellular carcinoma

Y Nishimura, T Nakatsura, S Senju - Nihon Rinsho Men'eki Gakkai …, 2008 - europepmc.org
tumor expressing mouse GPC3. Because of similarities in the binding peptide motifs between
H-2K(d) and HLA-A24 (… be useful for the immunotherapy of HLA-A24(+) patients with HCC …

A novel cytotoxic T-cell epitope presented by HLA-A24 molecule in hepatitis C virus infection

K Kurokohchi, K Arima, M Nishioka - Journal of hepatology, 2001 - Elsevier
… More than 50% of infected patients will develop chronic hepatitis, and some of those will
progress to hepatocellular carcinoma [3]. While the pathogenic mechanism of the hepatocellular

Identification of a novel HLA-A2-restricted mutated Survivin epitope and induction of specific anti-HCC CTLs that could effectively cross-recognize wild-type Survivin …

H Shen, HW Shao, XH Chen, FL Wu, H Wang… - Cancer Immunology …, 2013 - Springer
… To investigate whether Sur79L2 can induce Survivin-specific anti-hepatocellular carcinoma
(… In the HLA-A24 blocking experiment, anti-HLA-A24 mAb 22E1 markedly inhibited cytotoxic …

Coexpression of MAGE-A peptides and HLA class I molecules in hepatocellular carcinoma

N Roch, A Kutup, Y Vashist, E Yekebas… - Anticancer …, 2010 - ar.iiarjournals.org
… , if presented with human leukocyte antigen (HLA) molecules, … The MAGE-A expression profile
of hepatocellular carcinomas … immunotherapy, and HLA-A24 is commonly observed (60%) …

Dynamics of immature subsets of dendritic cells during antiviral therapy in HLA-A24–positive chronic hepatitis C patients

M Shiina, K Kobayashi, T Kobayashi, Y Kondo… - Journal of …, 2006 - Springer
… Hepatitis C virus (HCV) is one of the leading causes of chronic liver disease and hepatocellular
carcinoma worldwide. However, causes of the high persistent infection rate with HCV …

… of DC fused with allogeneic hepatocellular carcinoma cell line HepG2 and autologous tumor cells as potential cancer vaccines against hepatocellular carcinoma

DY Cao, JY Yang, SQ Yue, KS Tao, ZS Song… - Cellular …, 2009 - Elsevier
… Cytotoxic T lymphocytes (CTLs) induced by the fusion cells were able to kill autologous
HCC by HLA-A2- and/or HLA-A24-restricted mechanisms. CTL activity against shared TAAs …

Expression of the SART1 tumor-rejection antigen in hepatocellular carcinomas

S Yutani, S Shichijo, Y Inoue… - Oncology …, 2001 - spandidos-publications.com
… This study also showed that the SART1259 antigen on the HLA-A24 molecules of HCC
cells could be recognized by the CTLs, and the SART 1-derived peptide induced the HLAA24- …