… In contrast when the latter three peptides were examined, the data indicated that … features
characteristic of the peptides known to elicit HLA-DRlDwl-restricted T cells. When the peptide …

… allele, to insure that the inhibition was primarily measuring the binding characteristics of the
competitor peptide. This was confirmed by showing that the IC,, of unlabeled hemagglutinin …

… to capture general features of the relationship between peptides and HLA sequences and
interpret these in terms of a binding affinity. Such relationships can only by captured if the …

… a large scale dataset of over 17,000 HLA-peptide binding affinities for a set of 11 HLA DP
and DQ alleles. We also expanded our dataset for HLA DR alleles resulting in a total of 40,000 …

… Results from the second set of experiments, in which we compared the binding characteristics
of CLIP to DQ7, DQ9, and DR molecules, allowed similar conclusions: substitution of CLIP …

… of the peptide repertoires bound to HLA–DR molecules that are dif… to define structural features
of the shared peptides. Methods. … To evaluate similar features of the common peptides, we …

… We have previously described a novel approach to define sequence characteristics … peptide
library expressed on the surface of filamentous phage for binding to human DR molecules (…

… Positions and characteristics of amino acid residues important for HLA-I1 binding and …
peptides bound by HLA-DR molecules between DRBl*O405 and DRBl*O406 to search for peptide-…

… peptides other than CLIP and thereby modifies the peptide repertoire presented to T cells.
Here we report that DM can release a variety of peptides from HLA-DR molecules. … features of …

… the HLA-DR molecules in this study were incubated with biotinylated synthetic peptide and
… Conformational and structural characteristics of peptides binding to HLA-DR molecules. J. …