CRISPR/Cas9 for cancer therapy: hopes and challenges

M Martinez-Lage, P Puig-Serra, P Menendez… - Biomedicines, 2018 - mdpi.com
… Moreover, CRISPR-Cas9 can be employed to rapidly … Perhaps more importantly, the ability
of CRISPR-Cas9 to … use of CRISPR/Cas9 in therapeutic settings and major challenges that …

The hope and hype of CRISPR-Cas9 genome editing: a review

K Musunuru - JAMA cardiology, 2017 - jamanetwork.com
Importance Clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR-associated
protein 9 (CRISPR-Cas9) has garnered a great degree of attention since its first …

CRISPR/Cas9 for sickle cell disease: applications, future possibilities, and challenges

S Demirci, A Leonard, JJ Haro-Mora, N Uchida… - Cell Biology and …, 2019 - Springer
… using CRISPR/Cas9, addressing challenges and future perspectives of CRISPR/Cas9 as
a … Here we focus on the challenges of CRISPR-Cas9 editing, it’s implications, and future …

[HTML][HTML] Revitalizing oral cancer research: Crispr-Cas9 technology the promise of genetic editing

SV Sowmya, D Augustine, S Mushtaq… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
… that instill renewed hope for enhanced … of CRISPR/Cas-9 remains a challenge, with
lipid-mediated delivery systems showing promise (35). Despite these challenges, CRISPR/Cas-9 is …

The evolution of CRISPR/Cas9 and their cousins: hope or hype?

K Bhushan, A Chattopadhyay, D Pratap - Biotechnology letters, 2018 - Springer
Cas9 cleavage, has now been overcome by the use of Cpf1 nuclease. In this review, we
present an overview of CRISPR nucleases (Cas9 … and cons of CRISPR technology particularly …

CRISPR-Cas9 and the Promise of a Better Future

VL Raposo - European Journal of Health Law, 2019 - brill.com
… This article challenges the two main lines of argument against CRISPR-Cas9 (a method by
which … One can only hope that the continued use of gene editing to prevent certain genes will …

CRISPR/Cas9—A Promising Therapeutic Tool to Cure Blindness: Current Scenario and Future Prospects

I Ahmad - International Journal of Molecular Sciences, 2022 - mdpi.com
… In this review, recent progress and challenges of the CRISPR… -mediated genome editing
technology, there is a hope to … expressing the CRISPR/Cas9 components (Ad5-cas9 and Ad5-…

CRISPR/Cas9: prospects and challenges

F Zhang - Human gene therapy, 2015 - ncbi.nlm.nih.gov
… societal challenges and … CRISPR/Cas9, may turn out to be the tools we use for future
explorations. The tools themselves do not pose a threat, and it is my hope that the CRISPR/Cas9

Addressing challenges in the clinical applications associated with CRISPR/Cas9 technology and ethical questions to prevent its misuse

XJ Kang, CIN Caparas, BS Soh, Y Fan - Protein & cell, 2017 - academic.oup.com
… repeat (CRISPR)/CRISPR-associated 9 (Cas9) nuclease system … potential applications of
CRISPR/Cas9 technology and its … The CRISPR/Cas9 system has been successfully utilised to …

CRISPR/Cas9: A powerful genome editing technique for the treatment of cancer cells with present challenges and future directions

A Hazafa, M Mumtaz, MF Farooq, S Bilal, SN Chaudhry… - Life sciences, 2020 - Elsevier
… Based on accumulated data, we revealed that CRISPR/Cas9 … , and suggested that
CRISPR/Cas9 could be a potential … The present review also discussed the current challenges