… Pexiganan, topically administered to sufferers of diabetic foot ulcer, was as effective as oral
antibiotic treatment with ofloxacin, leading to a clinical cure or improvement in 90% of patients…

… novel antimicrobial therapies. As anti-infective agents, HDPs can be directly antimicrobial
and/… in the pathogen or target the host immune system rather than the pathogen. Furthermore, …

… cytokines and antimicrobial (host defence) … host immune responses [9, 10], hence therapy
based on immunomodulation to counteract viral immune evasion could be of great therapeutic …

… Antibiotic therapy was the standard treatment in sepsis clinical guidelines; however, a … -induced
sepsis has underscored the urgency of antibiotic resistance and the scarcity of effective …

… a significant lack of antibiotics for treatment of multidrug-resistant infections, new treatments
are needed that can replace and improve on current antibiotic therapies. HDPs have certain …

… the defense mechanisms utilized by host tissues, including the role of IL-17 in providing
immunity to oral candidiasis, the antimicrobial defense of … the potential for therapeutic benefit of …

… new era of antimicrobial therapies, giving rise to a multitude of antibiotics for the treatment of
… described roles of host defense peptides as well as the therapeutic progress of natural and …

… system plays a critical role in battling the bacterial infection, strategic targeting of the host
together with an appropriate antimicrobial treatment … Harnessing the innate host defenses thus …

… Antibiotic Therapy Tables 1 and 2 summarize our initial approach to treating gram-negative
bacillary meningitis in adults. The demonstration of impaired opsonization and phagocytosis …

… activate the innate immune system The host immune system evolved to recognize conserved
… , death, or in particular, antibiotic treatment against bacterial infection, these components …