Dynamic optimization of host defense, immune memory, and post-infection pathogen levels in mammals

E Shudo, Y Iwasa - Journal of Theoretical Biology, 2004 - Elsevier
delay required to have fully active immune cells. That is, we compare the case in which the
host’s immune system … immediately after infection (no time delay) and the case in which a …

Inducible defense against pathogens and parasites: optimal choice among multiple options

EMI Shudo, YOH Iwasa - Journal of Theoretical Biology, 2001 - Elsevier
… harm to the host body, and the length of time delay before the … the abundance of pathogen
in the host body at time t, and N … In the following, we consider the host's defense response to …

[HTML][HTML] Effects of time delay and space on herbivore dynamics: linking inducible defenses of plants to herbivore outbreak

GQ Sun, SL Wang, Q Ren, Z Jin, YP Wu - Scientific Reports, 2015 - nature.com
… Additionally, we revealed that interaction of time delaydelay may drive the resilience of
herbivore populations. Our findings highlight the close relationship between inducible defenses

Feedback control applied to survivability: a host-based autonomic defense system

OP Kreidl, TM Frazier - IEEE transactions on Reliability, 2004 - ieeexplore.ieee.org
… We can also insert random delays into the instrumented attack to vary the timing between
key attack steps. Variations on the attack are useful to determine the extent to which the …

The immune system and host defense against infections

JB Margolick, RB Markham… - … epidemiology: theory and …, 2014 - books.google.com
… similar across the immune systems of humans and of other animals, inferences from animal
models of disease often have direct applicability to human host defense and immune function…

Is it time to kill the survival curve? A case for disease progression factors in microbial pathogenesis and host defense research

RA Cramer, CH Kowalski - MBio, 2021 - Am Soc Microbiol
… many of our identified virulence and host defense factors (and the associated concepts
surrounding them) are relevant in established infection microenvironments. The many fungal-…

Host defenses in experimental scrub typhus: delayed-type hypersensitivity responses of inbred mice

TR Jerrells, JV Osterman - Infection and immunity, 1982 - Am Soc Microbiol
delayed-typehypersensitivity reactivity and resistance to intraperitoneal challenge were
examined. Delayed-… Delayed-type hypersensitivity reactivity declined thereafter, but resistance to …

Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression

Y Apidianakis, MN Mindrinos, W Xiao… - Proceedings of the …, 2005 - National Acad Sciences
… site, show that CF5 triggers host responses that protect against subsequent infection, because
PA14 mortality was significantly delayed in preinoculated flies, with a >4-h delay to 50% …

Delayed chemical defense: timely expulsion of herbivores can reduce competition with neighboring plants

P Backmann, V Grimm, G Jetschke… - The American …, 2019 - journals.uchicago.edu
… Time delays in plant … defenses, suggesting that there should be strong selection for rapid
responses. However, observed time delays between the onset of herbivory and defense

Malaria: host-defense mechanisms and complications

FA NEVA, JN SHEAGREN, NR SHULMAN… - Annals of Internal …, 1970 - acpjournals.org
… of delayed hypersensitivity. To my knowledge no studies of any of these phenomena have
been carried out in malaria. Cellular immunity, as differentiated from delayed … with delayed