… latter methods can only detect transcriptionally active virus integrants 2. … Integration loci
are associated with chromosome-fragile, DNase-hypersensitive and transcriptionally active sites…

… sites of transcriptional activity and chromatin marks of promoters/enhancers. Whether the
orientation of the HPV genome after integration … integrated HPV16 genome remains unknown. …

… and fragile sites, translocation break points, and transcriptional active … of HPV integration
sites in five penile carcinoma samples all positive for HPV16 and all containing integrated viral …

… HPV E6/E7 transcripts by RNA ISH is ideal because it confirms the presence of integrated and
transcriptionally active … , whereas most HNSCCs arising in nonoropharyngeal sites do not. …

… from clonal cultures to assess HPV persistence and transcription as described above. … can
be produced from the same integrated HPV genomes, provided the HPV SA sites (eg, SA 3358…

… RPL10, and transcriptionally repressed ZNF333 genes (… active histone marks near the
transcriptionally repressed ZNF333 gene was significantly lower than at the transcriptionally active …

… The localization of HPV integration sites in our cervical cancer series showed a single
integration site in most … Furthermore, as integration preferentially targets transcriptionally active …

… The HPV integration can result in uncontrolled transcription of viral genes and can influence
the balance of virus-cell interaction [74], thus, increasing cell susceptibility to other factors …

… regions of the HPV genome were integrated in these cell lines, the non-coding region and
an early region … ORFs are intact and transcriptionally active in all five cell lines examined. …

… data gathered on HPV integration loci in precancers and cancers have shown accumulation
of integration sites in transcriptional active and fragile chromosomal regions (19, 20) but …