The effect of HTLV-1 virulence factors (HBZ, Tax, proviral load), HLA class I and plasma neopterin on manifestation of HTLV-1 associated myelopathy tropical spastic …

H Tarokhian, M Taghadosi, H Rafatpanah, T Rajaei… - Virus research, 2017 - Elsevier
Neopterin production seems to be part of … main HTLV-1 virulence factors (PVL, Tax, and
HBZ) on the pathogenesis of HAM/TSP, host immune response (Ir)-genes and plasma neopterin

CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis

T Sato, A Coler-Reilly, A Utsunomiya… - PLoS neglected …, 2013 - journals.plos.org
… serum sIL-2R and plasma CXCL10 had the highest potential … ]>0.9), followed by plasma
CXCL9 and HTLV-1 proviral load in … -2R, plasma CXCL10, plasma CXCL9, and HTLV-1 proviral …

Neopterin in HIV-1 infection

B Wirleitner, K Schroecksnadel, C Winkler… - Molecular immunology, 2005 - Elsevier
… of neopterin as a marker in HIV-1 infection. Further evidence is increasing, that neopterin
The possible impact of neopterin derivatives and of other biochemical pathways induced by …

Neurofilament light in CSF and plasma is a marker of neuronal damage in HTLV-1–associated myelopathy and correlates with neuroinflammation

C Rosadas, H Zetterberg, A Heslegrave… - Neurology …, 2021 - AAN Enterprises
… Nf-L, CXCL10, and neopterin were measured by ELISA in 83 CSF samples obtained from
49 individuals living with HTLV-1/2. Plasma Nf-L was also measured by single molecule array. …

Neopterin as a predictive marker for disease progression in human immunodeficiency virus type 1 infection.

D Fuchs, TJ Spira, A Hausen, G Reibnegger… - Clinical …, 1989 - academic.oup.com
… Anti-HIV-1 antibod- ies, anti HTLV-I antibodiesand neopterin levels in parenteral drug … In
this study we have adapted the RIA for pineal ML (11) to measure ML in human plasma and …

Lessons from the cerebrospinal fluid analysis of HTLV-1-infected individuals: biomarkers of inflammation for HAM/TSP development

NL Freitas, YCP Gomes, FS Souza, RC Torres… - Viruses, 2022 - mdpi.com
… with HTLV-1 PVL (Figure 2B), and serum neopterin was associated with sTREM-2 in … -infected
individuals have reduced IL18 gene expression and plasma levels compared to HTLV-1-…

Following the clues: usefulness of biomarkers of neuroinflammation and neurodegeneration in the investigation of HTLV-1-associated myelopathy progression

FS Souza, NL Freitas, YCP Gomes, RC Torres… - Frontiers in …, 2021 - frontiersin.org
… infected CD4 + T-cells (HTLV-1 Tax + cells) were also … neopterin were elevated in HAM/TSP
patients. Most individuals in the control group and all HTLV-1 AC had CSF/serum neopterin

Human T lymphotropic virus 1-associated myelopathy: overview of human T cell lymphotropic virus-1/2 tests and potential biomarkers

M Puccioni-Sohler, AR Poton… - AIDS Research and …, 2022 - liebertpub.com
neopterin as candidate prognostic biomarkers for HTLV-1-… CXCL10 and neopterin as
biomarkers in HTLV-1-associated … in CSF and plasma is a marker of neuronal damage in HTLV-1-…

Pre-analytical long-term stability of neopterin and neurofilament light in stored cerebrospinal fluid samples

C Rosadas, GP Taylor - Clinical Chemistry and Laboratory Medicine …, 2023 - degruyter.com
… cell lymphotropic virus type-1 (HTLV-1) -associated myelopathy … One study showed that
neopterin in plasma is resistant to up … different concentrations of neopterin in plasma, when using …

Efficacy of l‐Arginine treatment in patients with HTLV1‐associated neurological disease

S Nozuma, E Matsuura, Y Tashiro… - Annals of Clinical …, 2023 - Wiley Online Library
… We also evaluated the effect of high doses of l-arginine on the plasma … that neopterin
concentrations in the CSF were significantly decreased after l-arginine administration. Neopterin is …