Evolution of the SARSCoV‐2 omicron variants BA. 1 to BA. 5: implications for immune escape and transmission

LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
… BA.1 replicated approximately 70 times higher than the Delta and Wuhan-Hu-1 variant in the
… human lung tissue compared to Wuhan-Hu-1 SARS-CoV-2 virus, which they hypothesised …

[HTML][HTML] Structural consequences of variation in SARS-CoV-2 B. 1.1. 7

DA Ostrov - Journal of cellular immunology, 2021 - ncbi.nlm.nih.gov
1: The location of mutated positions that distinguish the United Kingdom variant SARS-CoV-2
B.1.1.7 from Wuhan-Hu-1… -Hu-1 indicated on the primary structure of the coronavirus spike …

Antibodies elicited by SARS-CoV-2 infection and boosted by vaccination neutralize an emerging variant and SARS-CoV-1

L Stamatatos, J Czartoski, YH Wan, LJ Homad, V Rubin… - MedRxiv, 2021 - medrxiv.org
… donors neutralized Wuhan-Hu-1 and sporadically neutralized B.1.351, but a single
immunization boosted neutralizing titers against all variants and SARS-CoV-1 by up to 1000-fold. …

Impact of corticosteroid therapy on outcomes of persons with SARS-CoV-2, SARS-CoV, or MERS-CoV infection: a systematic review and meta-analysis

H Li, C Chen, F Hu, J Wang, Q Zhao, RP Gale, Y Liang - Leukemia, 2020 - nature.com
… respiratory syndrome coronavirus-2 (SARS-CoV-2) [1] which causes coronavirus infectious
coronavirus infections including SARS-CoV-2, severe acute respiratory syndrome (SARS) …

From the Wuhan-Hu-1 strain to the XD and XE variants: is targeting the SARS-CoV-2 spike protein still a pharmaceutically relevant option against COVID-19?

M Pavan, D Bassani, M Sturlese… - Journal of Enzyme …, 2022 - Taylor & Francis
… The SARS-CoV-2 S protein has experienced several mutations in the past two yearsCitation
48 , as reported in Tables 1 and 2 for the variants considered in our study. As can be noticed…

[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi - Nature Reviews Microbiology, 2021 - nature.com
… -first century 1 . At the end of 2019, a novel coronavirus designated as SARS-CoV-2 emerged
in … Being highly transmissible, this novel coronavirus disease, also known as coronavirus

[HTML][HTML] Genetic spectrum and distinct evolution patterns of SARS-CoV-2

…, J Shen, S Fang, K Li, J Liu, L Yang, CD Hu… - Frontiers in …, 2020 - frontiersin.org
… between SNVs among SARS-CoV-2 genomes from patients and bat coronavirus sequences,
we also aligned four bat coronavirus sequences to Wuhan-Hu-1 complete genome. The …

Plasma neutralization of the SARS-CoV-2 Omicron variant

F Schmidt, F Muecksch, Y Weisblum… - … England Journal of …, 2022 - Mass Medical Soc
… We measured neutralizing antibody titers against Wuhan-hu-1, PMS20, and omicron spike
pseudotypes in 169 plasma specimens from 47 persons with diverse exposures to SARS-CoV

Comparative analysis of the neutralizing activity against SARS-CoV-2 Wuhan-Hu-1 strain and variants of concern: Performance evaluation of a pseudovirus-based …

L D'Apice, M Trovato, G Gramigna, F Colavita… - Frontiers in …, 2022 - frontiersin.org
… in the detection of nAb response against SARS-CoV-2 Wuhan-Hu-1/D614G strains (wild
type, WT), Delta and Omicron BA.1 variants in residual anonymized serum samples collected …

Inhibition of SARS-CoV-2 wild-type (Wuhan-Hu-1) and Delta (B. 1.617. 2) strains by marine sulfated glycans

R Dwivedi, P Sharma, M Farrag, SB Kim… - …, 2022 - academic.oup.com
… for their anti-SARS-CoV-2 activity in a virus entry assay utilizing a SARS-CoV-2 pseudovirus
… In the current study, we investigate the anti-SARS-CoV-2 activity of MSGs comparatively …