[HTML][HTML] Associations between human aldosterone synthase CYP11B2 (-344T/C) gene polymorphism and antihypertensive response to valsartan in Chinese patients …

X Ji, H Qi, DB Li, RK Liu, Y Zheng… - International Journal of …, 2015 - ncbi.nlm.nih.gov
… The gene encoding aldosterone synthase, CYP11B2, is associated with … in aldosterone
synthesis could influence the antihypertensive response to Valsartan is not clear. A Chinese

A systemic review of the relationship between aldosterone synthase–344 C/T polymorphism and hypertension in Han

X Cheng, G Xu - Clinical and Experimental Hypertension, 2010 - Taylor & Francis
Chinese, despite the homogeneous patientsaldosterone synthase CYP11B2 -344 C/T risk
genotype CC and/or allele C and the susceptibility of essential hypertension in Han Chinese. …

[HTML][HTML] A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension

H Zhang, X Li, L Zhou, K Zhang, Q Zhang, J Li… - Medicine, 2017 - journals.lww.com
… Polymorphisms of the aldosterone synthase gene (CYP11B2) have been reported to … human
CYP11B2 and EH using a haplotype-based case–control study. A total of 1024 EH patients

[HTML][HTML] The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene

E Hui, MCW Yeung, PT Cheung, E Kwan, L Low… - BMC endocrine …, 2014 - Springer
… is the main mineralocorticoid hormone in humans that regulates sodium excretion and …
aldosterone synthase deficiency in a Chinese man and results of CYP11B2 analysis in the patient

Clinical characteristics of somatic mutations in Chinese patients with aldosterone-producing adenoma

FF Zheng, LM Zhu, AF Nie, XY Li, JR Lin, K Zhang… - …, 2015 - Am Heart Assoc
… in Chinese patients with aldosterone-producing adenoma remain unclear. In this study, we
performed DNA sequencing in 168 Chinese patients with aldosterone-… (aldosterone synthase

[HTML][HTML] Novel mutations in the CYP11B2 gene causing aldosterone synthase deficiency

N Li, J Li, Y Ding, T Yu, Y Shen… - Molecular …, 2016 - … .spandidos-publications.com
… is the principal mineralocorticoid hormone in humans, which is … Aldosterone synthase (CYP11B2),
a cytochrome P450 … However, to the best of our knowledge, only one Chinese patient

[HTML][HTML] Modulation of aldosterone levels by aldosterone synthase promoter polymorphism and association with eGFR decline in patients with chronic kidney disease

J Qian, J Zhong, M Yan, H Shi, C Hao… - Discovery …, 2018 - discoverymedicine.com
… Associations between human aldosterone synthase CYP11B2 (-344T/C) gene polymorphism
and antihypertensive response to valsartan in Chinese patients with essential hypertension…

Association between aldosterone synthase CYP11B2 polymorphism and essential hypertension in Chinese: a meta-analysis

X Cheng, G Xu - Kidney and Blood Pressure Research, 2009 - karger.com
… in the whole Chinese population was 1.12 in C allele patients compared with patients carrying
China, one of the centers of human civilization, comprises the largest geographical span, …

[HTML][HTML] Analysis of novel heterozygous mutations in the CYP11B2 gene causing congenital aldosterone synthase deficiency and literature review

H Miao, Z Yu, L Lu, H Zhu, RJ Auchus, J Liu, J Jiang… - Steroids, 2019 - Elsevier
… is the most important mineralocorticoid hormone in humans. … and hyponatremia; however,
our patient did not have an elevated … Here, we described a rare case of ASD in a Chinese male …

Haplotypic analyses of the aldosterone synthase gene CYP11B2 associated with stage‐2 hypertension in northern Han Chinese

D Gu, D Ge, J He, B Li, J Chen, D Liu, J Chen… - Clinical …, 2004 - Wiley Online Library
Human aldosterone synthase (CYP11B2), a steroid 11β-hydroxylase as well as an 18-hydroxylase
and an 18-oxidase, catalyses the terminal steps of aldosterone … hypertensive patients