… human brain in vitro. Multicellular in vitro models are beginning to replicate key aspects of
human brain … molecular and cellular insights into the pathogenesis of Alzheimer disease (AD). …

… distribution in the human brain, and the modifications of BDNF expression which occur in
the brain of individuals with Alzheimer’s disease and Parkinson’s disease. Our knowledge …

… In conclusion, following active Aβ42 immunization in human Alzheimer's disease, we
demonstrated that a lower plaque load is associated with an increase in cerebrovascular Aβ. …

… the cause(s) of Alzheimer disease. Numerous mouse transgenic lines … human APP transgenes
result in the deposition of Aβ peptide, similar but not identical to the Aβ peptide of human …

… in Alzheimer disease. We present multiple lines of evidence suggesting links between
neurodegenerative disease and glial cell types in human, including human-… disease genes in …

… of complement proteins in Alzheimer &sease (AD) brains, but … samples of post-mortem
human brain The transcripts for C3 … (PCR) amplification of brain derived complementary DNA (…

… onset Alzheimer disease (LOAD) human brain samples to uncover human-cortex expression
quantitative trait loci (eQTLs) that are relevant to both health and disease in the aged brain. …

… Lipids are key regulators of brain function and have been increasingly … Alzheimer disease
(AD). Here, a systems-based approach was employed to determine the lipidome of brain …

… exon 5 in human brain tissue. This product was more frequently detected in brain tissue
from … Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by …

Accumulation of phosphorylated tau is a key pathological feature of Alzheimer’s disease.
Phosphorylated tau accumulation causes synaptic impairment, neuronal dysfunction and …