3D virtual human atria: A computational platform for studying clinical atrial fibrillation

OV Aslanidi, MA Colman, J Stott, H Dobrzynski… - Progress in biophysics …, 2011 - Elsevier
… models for the human atria – the 3D virtual human atria. Primarily… in the human sinoatrial
node (SAN) and surrounding atrial … of the whole atria dissected from the Visible Human dataset. …

Pro‐arrhythmogenic effects of atrial fibrillation‐induced electrical remodelling: insights from the three‐dimensional virtual human atria

MA Colman, OV Aslanidi, S Kharche… - The Journal of …, 2013 - Wiley Online Library
… the segmentation of the 3D anatomical model of the human atria by taking into account
the presence of other electrophysiologically distinct regions in the atria, such as the AS, AVR, …

Electrical remodeling of the human atrium: similar effects in patients with chronic atrial fibrillation and atrial flutter

MR Franz, PL Karasik, C Li, J Moubarak… - Journal of the American …, 1997 - jacc.org
… whether chronic atrial fibrillation (AF) and atrial flutter in patients lead to electrical remodeling
of the human atrial myocardium, manifested by an abnormal relation between atrial cycle …

Structural correlate of atrial fibrillation in human patients

S Kostin, G Klein, Z Szalay, S Hein… - Cardiovascular …, 2002 - academic.oup.com
… of atrial fibrillation (AF). Methods: In 31 patients with AF undergoing a Maze procedure
and 22 patients in sinus rhythm (SR), biopsies were taken intraoperatively from the right …

Electrophysiological properties of the human atrium in atrial fibrillation

A Shimizu, OA Centurion - Cardiovascular research, 2002 - academic.oup.com
… on ectopic foci versus reentry as the mechanism underlying atrial fibrillation (AF) in humans
has continued. Recently, the mechanism of atrial fibrillation (AF) is considered to be a spiral …

Mechanisms for the initiation of human atrial fibrillation

DE Krummen, SM Narayan - Heart Rhythm, 2009 - Elsevier
Human atrial fibrillation (AF) likely encompasses a … 6 reaffirm our limited understanding of
human AF. Notable studies in the … Computer models of the human atria have shown that APD …

Electrophysiological characteristics of the human atria after cardioversion of persistent atrial fibrillation

C Pandozi, L Bianconi, M Villani, G Gentilucci… - Circulation, 1998 - Am Heart Assoc
Background—In animal models, induced atrial fibrillation shortens the atrial effective refractory
period (ERP) and reverses its physiological adaptation to rate. It is not clear whether this …

Dynamic electrophysiological behavior of human atria during paroxysmal atrial fibrillation

A Capucci, M Biffi, G Boriani, F Ravelli, G Nollo… - Circulation, 1995 - Am Heart Assoc
atrial fibrillation in the human atria. The electrophysiological mechanisms of atrial fibrillation
(AF) onset in humans have … to as dispersion of refractoriness or conduction within the atria, 1 …

Electrophysiological remodeling in human atrial fibrillation

DRV Wagoner - Pacing and clinical electrophysiology, 2003 - Wiley Online Library
atrial APs; 10 in human atria 11 and ventricle. I TO density is significantly greater in human
atrial … to the observation that APs are shorter in atrial myocytes. Kv4.3 protein is thought to be …

Effect of atrial fibrillation on atrial refractoriness in humans

EG Daoud, F Bogun, R Goyal, M Harvey, KC Man… - Circulation, 1996 - Am Heart Assoc
… have demonstrated that atrial fibrillation (AF) induces remodeling of the atria and that this …
In humans, clinical observations suggest that AF promotes changes in the atria. Chronic AF …