… on the biology of human Tfh cells, and the establishment of … cells in human autoimmune
diseases, and discuss the factors that promote exaggerated Tfh cell responses in humans…

… autoimmune diseases. In this Perspective article, I discuss the increase in circulating T FH
cells seen in autoimmune … I consider the multistep regulation of T FH cell differentiation by the …

… cell activation in autoimmune diseases. We discuss Tph cells as a promising therapeutic
strategy in autoimmunity … tracking Tph cells in blood as a biomarker to quantify aberrant T cell–B …

… within human cTfh cells, and discuss their alterations in patients with autoimmune diseases.
… mechanisms associated with the aberrant Tfh responses in human autoimmune diseases. …

… In comparison with our understanding of T FH cells, knowledge of the T helper cells that
drive the extrafollicular response is relatively limited. Within 2 days after primary immunization, …

… Tfh-like cells, which are more accessible than Tfh cells in tissues, … these cells in the context
of human autoimmune disorders. … cells have been described in a broad range of autoimmune …

… of autoimmune diseases. Here we first describe evidence of aberrant T FH responses in mouse
and human autoimmunity… with aberrant T FH responses in human autoimmune diseases. …

… helper cells with different functions and patterns of cytokine secretion were identified in both
mice and humans… from autoimmunity to asthma 6, and T follicular helper (Tfh) cells that enter …

… -reactive B cells, favoring the development of autoimmunity. … cell engaged with a self-antigen
interacts with a T helper cell, … T helper cells are deeply involved in the breakdown of B cell …

… in autoimmunity ( 11 ). In this review, we will cover studies of the differentiation and function
of Tfh and Tfr cells, and their potential roles in autoimmune diseases. Tfh cell development …