Control of B-cell activation The B-cell antigen receptor complex Page 1 Control of B-cell
activation B-cell antigen receptors, namely the membrane-bound forms of immunoglobulin, not …

… As noted earlier, the antigen receptor on immature and mature B cells comprises a clonally
distributed membrane-bound sIg that is noilcovale~itly associated with disulfide-linked Ig-oe …

… On human B cells the antigen receptor complex is composed of the membrane form of the
… of normal B cells and chronic lymphocytic leukemia B cells express (analogous to T cells) …

… BCR complex, we have used the human Burkitt lymphoma line Ramos as a model system. …
cell line represents mature, IgM bearing B cells (32). The known subunits of the BCR complex…

… of human B lymphocytes (16). Other surface receptors that co-cluster with the mIg receptor
complex can also have important modulatory effects on B cell activation via the mIg signaling …

… complex. When analyzing human B cells, we found that sIgM associates not only with human
… Here we report that the 150-kDa component associated with the human IgM-BCR complex …

… Full-length human mb-1 cDNA … antigen receptor also contains a heterodimer that seems to
have the same (8component but a different a-component from that of the IgM antigen receptor"…

… human B-cell antigen receptor complex (BCR) and its role in the development of normal and
neoplastic human B cells… components of the B cell antigen receptor complex of class IgD …

… In summary, we have shown that mIgM on human B lymphocytes is non-covalently associated
with a disulfidelinked dimer of N-glycosylated subunits of 47 and 37 kDa that most likely …

… the different antigen receptors on human B cells and … antigen receptors differ in their coupling
to intraceUular signaling pathways. Recently, we have shown that mlgM on human B cells …