Tissue-resident memory T cells populate the human brain
J Smolders, KM Heutinck, NL Fransen… - Nature …, 2018 - nature.com
… by tissue-resident memory T cells (T RM cells), which are adapted … human white matter-derived
brain CD8 + T cells can be subsetted into CD103 − CD69 + and CD103 + CD69 + T cells …
brain CD8 + T cells can be subsetted into CD103 − CD69 + and CD103 + CD69 + T cells …
Human memory T cells: generation, compartmentalization and homeostasis
… current knowledge of human memory T cells. We describe … investigate how memory T cells
are organized in human tissue … of T cell subsets and their specificities within the human body …
are organized in human tissue … of T cell subsets and their specificities within the human body …
Resident memory T cells in human health and disease
RA Clark - Science translational medicine, 2015 - science.org
… memory T cells, exploring how these cells contribute to healthy immune function and discussing
what is known about how these cells contribute to human … all T and B cells in the body, …
what is known about how these cells contribute to human … all T and B cells in the body, …
Regional and mucosal memory T cells
BS Sheridan, L Lefrançois - Nature immunology, 2011 - nature.com
… The human body is separated from the outside world by barrier surfaces that carry out many
… contain most the body's memory T cells. Other tissues, such as the brain, bone marrow and …
… contain most the body's memory T cells. Other tissues, such as the brain, bone marrow and …
Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice
…, F van der Meer, N Page, B Klimek… - Science translational …, 2019 - science.org
… brains imprinted a chronic inflammatory signature that consisted of brain-resident memory
T cells … In mouse and human brain, CCL5 + T RM were located predominantly to sites of …
T cells … In mouse and human brain, CCL5 + T RM were located predominantly to sites of …
The emerging role of resident memory T cells in protective immunity and inflammatory disease
… of memory T cells: tissue-resident memory T cells, or T RM cells. Under physiological
conditions, T RM cells … Whether such T RM cells can form in human brain after viral infection is …
conditions, T RM cells … Whether such T RM cells can form in human brain after viral infection is …
Tissue‐resident memory T cells
H Shin, A Iwasaki - Immunological reviews, 2013 - Wiley Online Library
… tissues in the body based on patterns of memory T-cell … CCR7+ memory T cells, termed central
memory T cells (T … , while CCR7 − memory T cells, named effector memory T cells (T EM ), …
memory T cells (T … , while CCR7 − memory T cells, named effector memory T cells (T EM ), …
Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory
A Okhrimenko, JR Grün, K Westendorf… - Proceedings of the …, 2014 - National Acad Sciences
… This is a drastic reversal of the current concept that memory T cells recirculate throughout
the body to find their cognate antigen, presented to them by APCs in SLOs. If …
the body to find their cognate antigen, presented to them by APCs in SLOs. If …
CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer
MK Callahan, KA Williams, P Kivisäkk, D Pearce… - Journal of …, 2004 - Elsevier
… Chemokines and their receptors may be implicated in leukocyte ingress into brain during …
+ memory T lymphocytes during diapedesis, we used an in vitro model of the blood–brain …
+ memory T lymphocytes during diapedesis, we used an in vitro model of the blood–brain …
Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions
…, MCJ Vincenten, EBM Remmerswaal, T Kuhlmann… - Brain, 2020 - academic.oup.com
… Here we provide an extensive analysis of the phenotypic profile and spatial localization of
human brain T cells in relation to the post-mortem pathology of advanced multiple sclerosis. …
human brain T cells in relation to the post-mortem pathology of advanced multiple sclerosis. …
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