Wide-field quantitative micro-elastography of human breast tissue

WM Allen, KM Kennedy, Q Fang, L Chin… - Biomedical Optics …, 2018 - opg.optica.org
… , qualitative (strain) micro-elastograms and quantitative (… wide-field quantitative micro-elastography
can extend the … in either OCT or qualitative micro-elastography and, in addition, can …

Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography

KM Kennedy, L Chin, RA McLaughlin, B Latham… - Scientific reports, 2015 - nature.com
… a qualitative indication of mechanical properties. To overcome this limitation, we present
quantitative micro-elastography, … a compliant stress sensor to image tissue elasticity. The sensor …

Diagnostic accuracy of quantitative micro-elastography for margin assessment in breast-conserving surgery

KM Kennedy, R Zilkens, WM Allen, KY Foo, Q Fang… - Cancer research, 2020 - AACR
… indirect and qualitative measure of elasticity, introduction of a stress sensing technique to
map the local stress in 2D at the tissue surface, has enabled quantitative micro-elastography (…

Quantitative Micro-Elastography Enables In Vivo Detection of Residual Cancer in the Surgical Cavity during Breast-Conserving Surgery

P Gong, SL Chin, WM Allen, H Ballal, JD Anstie, L Chin… - Cancer Research, 2022 - AACR
Quantitative micro-elastography (QME) is an optical imaging technique that visualizes
microscale stiffness in three dimensions (3D) to depths of ∼1 mm in breast tissue (20). QME is …

Analysis of sensitivity in quantitative micro-elastography

J Li, MS Hepburn, L Chin, A Mowla… - Biomedical Optics …, 2021 - opg.optica.org
Quantitative micro-elastography (QME) is an emerging technique to map tissue elasticity
into micro-scale images, termed micro-elastograms. QME is an extension of compression …

Handheld probe for quantitative micro-elastography

Q Fang, B Krajancich, L Chin, R Zilkens… - Biomedical Optics …, 2019 - opg.optica.org
… QME scans performed on human breast tissue specimens. For each specimen, quantitative
micro-… the ability to distinguish stiff cancerous tissue from surrounding soft benign tissue. …

Clinical feasibility of optical coherence micro-elastography for imaging tumor margins in breast-conserving surgery

WM Allen, KY Foo, R Zilkens, KM Kennedy… - Biomedical optics …, 2018 - opg.optica.org
… , quantitative micro-elastography, a thin compliant layer is placed between the imaging
window and the specimen to measure tissue … work investigating quantitative micro-elastography, …

Finger-mounted quantitative micro-elastography

RW Sanderson, A Curatolo, P Wijesinghe… - Biomedical optics …, 2019 - opg.optica.org
… healthy and diseased tissue is often … breast tissue is up to seven times stiffer than adipose
tissue [39], likewise, cirrhotic liver tissue is approximately twice as stiff as healthy liver tissue

In vivo volumetric quantitative micro-elastography of human skin

S Es'Haghian, KM Kennedy, P Gong, Q Li… - Biomedical optics …, 2017 - opg.optica.org
… Figure 4 shows in vivo quantitative micro-elastography results acquired from a mole on
the forearm of a 31-year-old female subject. A photograph of the mole is shown in Fig. 4(a). …

Analysis of friction in quantitative micro-elastography

KL Metzner, Q Fang, RW Sanderson… - Biomedical Optics …, 2023 - opg.optica.org
Quantitative micro-elastography (QME) is a compression-based optical coherence elastography
technique capable of measuring the mechanical properties of tissue on the micro-scale. …