… In the present study of isolated human bronchus rings, we … muscarinic antagonist (ipratropium).
We primarily investigated the potency, onset and duration of action of these antagonists …

… Epithelial cells from freshly isolated human bronchi contain 23±6 pmol acetylcholine per
gram … Atropine is a nonselective muscarinic antagonist with similar affinities for all five …

… Influence of beclomethasone (A and B) and glycopyrronium (C and D) on the contractile
tone of human segmental bronchi (A and C) and on the luminal area of human bronchioles (B …

… More recently we have confirmed that these muscarinic receptors are of the ml-receptor
subclass in human lungs using specific cDNA probes. Northern analysis of human lung …

… Also, nonselective muscarinic antagonists, by blocking the postjunctional M 2 receptor-…
bronchospasm than M 3 receptor-selective antagonists, yet the relative clinical importance of this …

… In the human lung, muscarinic receptors are predominantly expressed by smooth muscle …
being inhibited by aclidinium, a long-acting muscarinic antagonist, or atropine [58]. Animals …

… histamine release in human airways. In the present experiments bronchi from nonasthmatics
… We conclude that in human airways stimulation of muscarinic receptors strongly inhibits the …

… Cholinergic activity of the lung is more pronounced in large … Muscarinic antagonists have
proved useful in the treatment of … role of muscarinic receptors and their antagonists in human …

… Although muscarinic receptor proteins have not been characterized in human muscle, … been
detected in human bronchi (11), supporting the hypothesis that human airways express both …

… Isolated human bronchi obtained from 26 patients with lung cancer were separated into two
… /5 min in group 1 bronchi, in contrast to only 1730 ± 240 pmol/g/5 min in group 2 bronchi (p < …