Human cancer cell lines: fact and fantasy

JRW Masters - Nature reviews Molecular cell biology, 2000 - nature.com
human cancer cell lines are transplanted subcutaneously into immunodeficient mice (such as
the nude strain), most can form tumours. Of 127 human cancer cell … of cancer cell lines with …

Culture characteristics of four permanent lines of human cancer cells

AE Moore, L Sabachewsky, HW Toolan - Cancer research, 1955 - AACR
The cultural and morphological characteristics of three strains of human epidermoid cancer
cells (H.Ep. #1, H.Ep. #2, and H.Ep. #3) and one human embryonal rhabdomyosarcoma (H.…

miRNAs in human cancer

TA Farazi, JI Spitzer, P Morozov… - The Journal of …, 2011 - Wiley Online Library
… , the oestrogen receptor-positive ductal cell line MCF7, human fat and blood (Farazi and …
the profile of a human cancer by simply combining tumour cell line and human fat profiles at …

A comprehensive transcriptional portrait of human cancer cell lines

C Klijn, S Durinck, EW Stawiski, PM Haverty… - Nature …, 2015 - nature.com
Cancer cell lines have transformed our understanding of human cancer cell biology, from …
the disease heterogeneity that defines the cancer patient population. Deep analysis of …

Inhibition of telomerase limits the growth of human cancer cells

WC Hahn, SA Stewart, MW Brooks, SG York, E Eaton… - Nature medicine, 1999 - nature.com
… into various cell lines (Fig. 1b). The infected cell lines included the human cancer cell lines
… spontaneously immortalized, telomerase-positive human embryonic kidney cells 33 (HA-1). …

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

A Lujambio, S Ropero, E Ballestar, MF Fraga… - Cancer research, 2007 - AACR
Human cancer cell lines and primary tumor samples. HCT-116 colon cancer cells and …
All the other human cancer cell lines (n = 30) were obtained from the American Type Culture …

A systematic profile of DNA methylation in human cancer cell lines

MF Paz, MF Fraga, S Avila, M Guo, M Pollan… - Cancer research, 2003 - AACR
… The 70 human cancer cell lines used in this study were obtained from the American Type
Culture Collection (Rockland, MD), the German Collection of Microorganisms and Cell

Antioncogenes and human cancer.

AG Knudson - Proceedings of the National Academy of …, 1993 - National Acad Sciences
… These discoveries have illuminated our understanding of human cancer considerably
and have revealed a group of genes that is important in cellular and developmental biology, …

Systematic variation in gene expression patterns in human cancer cell lines

DT Ross, U Scherf, MB Eisen, CM Perou, C Rees… - Nature …, 2000 - nature.com
Cancer Institute's Developmental Therapeutics Program (DTP) has carried out intensive studies
of 60 cancer cell … features of the cells related to cancer and chemotherapeutic sensitivity, …

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

F Bunz, PM Hwang, C Torrance… - The Journal of …, 1999 - Am Soc Clin Investig
We have examined the effects of commonly used chemotherapeutic agents on human colon
cancer cell lines in which the p53 pathway has been specifically disrupted by targeted …