DNA methylation alterations in human cancers

S Wang, W Wu - Epigenetics in Human Disease, 2018 - Elsevier
methylation level. Then, we summarized the mechanisms by which DNA methylation functions
in human cancers. … of DNA methylation in the initiation, development, and metastasis of …

Alterations of DNA methylation and clinicopathological diversity of human cancers

Y Kanai - Pathology international, 2008 - Wiley Online Library
alterations of DNA methylation and human cancers. Correlation between the etiological
backgrounds of human cancers and alterations of DNA methylation, … DNA methylation alterations

Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state

Y Kanai, S Hirohashi - Carcinogenesis, 2007 - academic.oup.com
… We focused on abnormalities of DNMTs underlying alterations of DNA methylation in human
cancers. The expression level of DNMT1 mRNA was first examined by quantitative reverse …

Cancer epigenetics: DNA methylation and chromatin alterations in human cancer

M Esteller - … on Cancer: New Trends in Cancer for the 21st Century …, 2003 - Springer
hypermethylation events are truthfully relevant for humanhypermethylation profiles for
every form of human tumors has … cancer patients based in our knowledge of DNA methylation. …

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

M Esteller, JG Herman - The Journal of Pathology: A Journal of …, 2002 - Wiley Online Library
… In fact, epigenetic changes, particularly DNA methylation, are susceptible to change and are
… increase the risk of cancer. The delicate organization of methylation and chromatin states …

Mechanisms of human DNA methylation, alteration of methylation patterns in physiological processes and oncology

A Sergeeva, K Davydova, A Perenkov, M Vedunova - Gene, 2023 - Elsevier
… of the genome with local hypermethylation is observed. In this review… DNA methylation and
demethylation in humans, the structure and distribution of CpG islands, the role of methylation

Defining driver DNA methylation changes in human cancer

GP Pfeifer - International journal of molecular sciences, 2018 - mdpi.com
… This modification occurs predominantly at CpG dinucleotide … DNA methylation changes
observed in human cancers. These events include CpG-island-specific DNA hypermethylation

DNA methylation aberrancies as a guide for surveillance and treatment of human cancers

G Liang, DJ Weisenberger - Epigenetics, 2017 - Taylor & Francis
… display DNA methylation alterations that correlate with tumor … of DNA methylation-derived
gene expression alterations are … DNA methylation alterations positively correlate with tumor

Characterizing DNA methylation alterations from the cancer genome atlas

DJ Weisenberger - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
… , and DNA methylation alterations in 30 cancer types. TCGA … potential to shape cancer
diagnostic and treatment strategies. … DNA methylation alterations in human cancers from TCGA. …

[HTML][HTML] Pan-cancer landscape of aberrant DNA methylation across human tumors

S Saghafinia, M Mina, N Riggi, D Hanahan, G Ciriello - Cell reports, 2018 - cell.com
… of our approach to explore DNA methylation changes in pediatric tumors, which frequently …
epigenomic modifications. Our results provide a pan-cancer map of aberrant DNA methylation