… and integrated viral DNA [2, 27–29]. The rate of HPV integration in other anogenital cancers
… One study reports that almost 80% of anal carcinomas contain integrated HPV; however, the …

… ) have been associated with many human cancers in clinical … This study suggests that HPV
integration is still a significant … biomarkers for the early diagnosis of HPV-related cancers. …

… data for HPV-related oral and oropharyngeal cancers. … HPV integration sites and the
relationship of integration to viral-host fusion transcripts and whether integration is required for HPV-…

… The aim of this study was to identify the chromosomal location of HPV integration sites …
integrated viral genomes into the human chromosome. DNA samples were amplified using a HPV-…

… potential HPV integration events that have occurred in the human … of HPV integration both
within the HPV and the human genome. … WGS in other HPV-positive human cancer cell lines, …

… papillomavirus (HPV). Here we report a striking association between HPV integration and
adjacent host genomic structural variation in human cancer cell lines and primary tumors. …

… of published integration sites in HPV-related cancers and … the functional elements of the
human genome, such as the … of the human host genome surrounding HPV integration sites …

… HPV-16 plasmid genomes, HPV sequences are integrated in the majority of these cancers in
a manner similar to findings for cervical cancers and … We also found that integrated HPV-16 …

… Light blue arrows: genes affected by HPV integration; red arrows: HPV fusion transcripts
described in this work; grey arrows: HPV fusion transcripts described by Kraus et al. 2008; …

… Interesting to note, we found HPV integration in the following fragile regions—(1p, 1q, 2p,
2q, 3p, 3q, 4p, 4q, 5p, 5q, 7q, 9q, 10q, 11p, 11q, 12p, 12q, 13q, 15q, 17q, 18q, 22q, Xp and Xq) …