The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications

Y Toh, GL Nicolson - Clinical & experimental metastasis, 2009 - Springer
… and progression of a wide variety of cancers [6–8]. In this … human cancers and the important
molecular mechanisms that are currently known by which MTA proteins exert their functions. …

[图书][B] Molecular biology of human cancers

WA Schulz - 2023 - Springer
… Similarly, the function of specific signal transduction pathways (“cancer pathways”) and … )
experiments that underlie our knowledge on cancer molecular biology in any appropriate detail. …

The novel roles of circRNAs in human cancer

Q Shang, Z Yang, R Jia, S Ge - Molecular cancer, 2019 - Springer
… sponge of miR-7 and inhibits functions of miRNA, which in turn positively regulates miR-7 …
sponge function in the mammalian brain [35]. This study reveals a molecular regulatory …

The role of MicroRNAs in human cancer

Y Peng, CM Croce - Signal transduction and targeted therapy, 2016 - nature.com
… to mediate tumor suppressive function. The p53 is a tumor suppressor encoded by the
gene TP53, one of the most commonly mutated genes in human cancers. p53-regulated …

The functional role of long non-coding RNA in human carcinomas

EA Gibb, CJ Brown, WL Lam - Molecular cancer, 2011 - Springer
… variety of human cancers, however the biological functions of … the molecular mechanisms by
which these RNA species function… the emerging functional role of lncRNAs in human cancer. …

Role of p53 in cell death and human cancers

T Ozaki, A Nakagawara - Cancers, 2011 - mdpi.com
… : p53 is a nuclear transcription factor with a pro-apoptotic function. Since over 50% of human
cancers carry loss of function mutations in p53 gene, p53 has been considered to be one of …

Emerging roles of claudins in human cancer

MJ Kwon - International journal of molecular sciences, 2013 - mdpi.com
… Claudin-1 is one of the most dysregulated claudins in human cancers, and its crucial role
in various cancers has been described (Table 3). Claudin-1 can function as a cancer-…

Circular RNAs function as ceRNAs to regulate and control human cancer progression

Y Zhong, Y Du, X Yang, Y Mo, C Fan, F Xiong, D Ren… - Molecular cancer, 2018 - Springer
… , especially in the progression of human cancer. … functions and may serve as a target
for cancer treatment. In the future, targeting of circRNA may be used not only for direct anti-cancer

The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment—twenty-seventh GHA Clowes …

IB Weinstein - Cancer research, 1988 - AACR
… We hypothesize that the usual function of the regulatory … , human populations are often
exposed to both types of agents. I think it is likely, therefore, that certain forms of human cancer

Viruses and human cancers: a long road of discovery of molecular paradigms

MK White, JS Pagano, K Khalili - Clinical microbiology reviews, 2014 - Am Soc Microbiol
… tool to study molecular and cellular mechanisms in the field of cancercancer. In this review,
we consider the evidence for the involvement of viruses in human cancer and the molecular