Emerging roles of MTA family members in human cancers

R Kumar, RA Wang, R Bagheri-Yarmand - Seminars in oncology, 2003 - Elsevier
… This article reviews the current status of MTA biochemistry and its implications for tumor …
correlated with aggressiveness in several types of human cancers.3 However, its expression is …

The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications

Y Toh, GL Nicolson - Clinical & experimental metastasis, 2009 - Springer
… genesis and progression of a wide variety of cancers [6–8]. In … MTA family members in
human cancers and the important molecular mechanisms that are currently known by which MTA

Clinical implications of MTA proteins in human cancer

E Kaur, S Gupta, S Dutt - Cancer and Metastasis Reviews, 2014 - Springer
… research, several biological functions of the MTA family of proteins have been discovered. …
Most importantly, given its important role in cancer progression, the possibility of MTA family

MTA family of proteins in prostate cancer: biology, significance, and therapeutic opportunities

AS Levenson, A Kumar, X Zhang - Cancer and Metastasis Reviews, 2014 - Springer
… of the role of MTA family members, particularly MTA1, with a special emphasis on prostate
cancer. The interest for the role of MTA1 in prostate cancer was boosted from our initial …

Unravelling the complexity and functions of MTA coregulators in human cancer

DQ Li, R Kumar - Advances in cancer research, 2015 - Elsevier
MTA family of coregulatory proteins in human cancer has profoundly grown. MTA proteins
consist of six family … to regulation of gene expression in cancer cells. Substantial experimental …

Molecular functions and significance of the MTA family in hormone-independent cancer

Z Ning, J Gan, C Chen, D Zhang, H Zhang - Cancer and Metastasis …, 2014 - Springer
… of the MTA family, focusing on hormone-independent cancers. … MTA family-related signaling
pathways in different cancers. … been reported in various human cancers including colon [117]…

Structure, expression and functions of MTA genes

R Kumar, RA Wang - Gene, 2016 - Elsevier
… The overexpression of MTA family members in human cancer is generally accompanied by
increased mRNA and/or protein and infrequently associated with copy number amplification (…

Subcellular localization of MTA proteins in normal and cancer cells

J Liu, H Wang, C Huang, H Qian - Cancer and Metastasis Reviews, 2014 - Springer
… We review the sub-cellular localization patterns of the MTA family members and give a …
correlated with the malignant properties of human cancers, the molecular functions of MTA1 …

Properties and clinical relevance of MTA1 protein in human cancer

Y Toh, GL Nicolson - Cancer and Metastasis Reviews, 2014 - Springer
… of the members of a gene family (MTA gene family) and the products of the MTA genes, the
… properties of human cancers, strongly suggesting that MTA1 and possibly other MTA proteins …

Physiological functions of MTA family of proteins

N Sen, B Gui, R Kumar - Cancer and Metastasis Reviews, 2014 - Springer
… in rat mammary gland metastatic and human breast cancer cell lines [1, 2]. … MTA family is
predominantly derived from cancer-based model systems. However, our understanding of MTA’…