Human carboxylesterase isozymes: catalytic properties and rational drug design
T Imai - Drug metabolism and pharmacokinetics, 2006 - jstage.jst.go.jp
… isozymes are classiˆed into four main CES groups (CES1-CES4) and several subgroups …
of human CES and the contribution of CES isozymes in the hydrolase activity of the human liver …
of human CES and the contribution of CES isozymes in the hydrolase activity of the human liver …
[HTML][HTML] Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs
M Hosokawa - Molecules, 2008 - mdpi.com
… It is interested that CES1G family isozymes only found in rats and mice, not found in human.
Although high level of hydrolase activity can be detected in the blood of the rats and mice, …
Although high level of hydrolase activity can be detected in the blood of the rats and mice, …
Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes
T Fukami, M Nakajima, T Maruichi… - Pharmacogenetics …, 2008 - journals.lww.com
… We sought to clarify the confusing gene structure of human CES1A. … here significantly
increase our understanding about the gene structure and expression properties of human CES1A. …
increase our understanding about the gene structure and expression properties of human CES1A. …
Human carboxylesterases and their role in xenobiotic and endobiotic metabolism
MK Ross, JA Crow - Journal of biochemical and molecular …, 2007 - Wiley Online Library
… human carboxylesterase 1 protein; HLC, pooled human liver cytosol; HLM, pooled human
liver microsomes; hCE2, human carboxylesterase 2. … Human carboxylesterase isozymes: …
liver microsomes; hCE2, human carboxylesterase 2. … Human carboxylesterase isozymes: …
Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine
T Imai, M Taketani, M Shii, M Hosokawa… - Drug metabolism and …, 2006 - ASPET
… The purpose of the present study is to demonstrate the relative contributions of CES
isozymes in the hydrolase activity of microsomes from human liver and small intestine, and to …
isozymes in the hydrolase activity of microsomes from human liver and small intestine, and to …
Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans
M Hosokawa, T Maki, T Satoh - Archives of biochemistry and biophysics, 1990 - Elsevier
… isozymes of carboxylesterase, designated as RLl, RL2, and RHl (10). These three
carboxylesterase isozymes … the characteristics of carboxylesterase isozymes purified from liver …
carboxylesterase isozymes … the characteristics of carboxylesterase isozymes purified from liver …
Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver
H Schwer, T Langmann, R Daig, A Becker… - Biochemical and …, 1997 - Elsevier
… isoenzymes. Overexpression and purification of the iCE will enable the 8 of the human
carboxylesterase … using antibodies carboxylesterase with those of three carboxylesterases that …
carboxylesterase … using antibodies carboxylesterase with those of three carboxylesterases that …
Molecular aspects of carboxylesterase isoforms in comparison with other esterases
T Satoh, M Hosokawa - Toxicology letters, 1995 - Elsevier
… carboxylesterases using cDNAs of carboxylesterase isozymes purified from 9 animal species
and human … in the contents of the carboxylesterase isozymes by immunological assay with …
and human … in the contents of the carboxylesterase isozymes by immunological assay with …
An activity-based fluorogenic probe enables cellular and in vivo profiling of carboxylesterase isozymes
SY Liu, RY Qu, RR Li, YC Yan, Y Sun… - Analytical …, 2020 - ACS Publications
… Carboxylesterases (CEs) exist as multiple types of isomers in humans, and two major types
… method for simultaneous determination of CE isozymes in complex biological systems and …
… method for simultaneous determination of CE isozymes in complex biological systems and …
Carboxylesterase in the liver and small intestine of experimental animals and human
M Taketani, M Shii, K Ohura, S Ninomiya, T Imai - Life sciences, 2007 - Elsevier
… human liver and small intestine are compared with those in several experimental animals
(monkeys, dogs, rabbits and rats) using specific substrates for human CES isozymes … isozymes …
(monkeys, dogs, rabbits and rats) using specific substrates for human CES isozymes … isozymes …
相关搜索
- human carboxylesterase isozymes rational drug design
- carboxylesterase isozymes human liver
- human carboxylesterase 2 gene
- recombinant human carboxylesterase
- detection of human carboxylesterase
- carboxylesterase isozymes metabolic activation of prodrugs
- human carboxylesterases differential hydrolysis
- probe substrate human carboxylesterase
- human carboxylesterases discovery of natural inhibitors
- genomic translocations human carboxylesterase
- regulatory element human carboxylesterase
- carboxylesterase isozymes fluorogenic probe
- cellular imaging human carboxylesterase
- human carboxylesterases drug metabolism
- nucleotide polymorphisms human carboxylesterase
- human carboxylesterases enzymatic activity