4 天前 - … transcriptional effects and genome-wide DNA methylation changes caused by long-…
DNA methylation changes in human adenocarcinoma alveolar basal epithelial A549 cells …

4 天前 - … regulate transcription, signaling, DNA methylation and repair, … is also increased in
most forms of cellular stress (4). … ’s myriad roles in cellular physiology and in human disease. …

4 天前 - … the most dynamic period in human development. This time … were related to DNA
methylation in buccal cells collected at … to estimate age from DNA methylation, our study aims to …

4 天前 - … Cell type assignments were predicted using Azimuth with the human kidney
reference dataset. The snATAC-seq data was processed with ArchR v1.0.1, which performed …

7 天前 - … We found that human naïve CD8 + T cells, which decrease in humans during aging,
… Given the overlap of DNA methylation signatures of cellular aging and CD8 + differentiation…

7 天前 - … In summary, this genome-wide DNA methylation study of diagnostic prostate
tumours has identified 16 dmCpGs that distinguish tumour from adjacent benign tissue in both …

8 天前 - The inheritance of parental histones across the replication fork is thought to mediate
epigenetic memory. Here, we reveal that fission yeast Mrc1 (CLASPIN in humans) binds H3…

8 天前 - … Recent studies have shown that its expression suppresses T cells activation and
promote tumor … the promising potential of ITPRIPL1 as a therapeutic target for human cancer. …

9 天前 - … JEG-3 cells. BSAS analysis indicated altered DNA methylation profile at the site-specific
CpGs within the DMRs of the {H19/IGF2} domain. The methylation levels of several …

11 天前 - … as DNA methylation, ncRNA m6A, and mRNA m6A. RNA m6A modification is
critical for colorectal organ homeostasis, and its disruption leads to inflammatory disorders and …