Oestrogen and colorectal cancer: mechanisms and controversies
PA Foster - International journal of colorectal disease, 2013 - Springer
… Evidence also suggests that protective effects are modulated through oestrogen receptor …
allows for an increase in intracellular sulphated oestrogen concentrations, providing substrate …
allows for an increase in intracellular sulphated oestrogen concentrations, providing substrate …
Estrogen receptors and human disease: an update
KA Burns, KS Korach - Archives of toxicology, 2012 - Springer
… ovarian tissue, but often ovarian cancers exhibit cytoplasmic ERβ immunopositivity. ERβ
levels … 1 (IGF1) and estrogens is correlated with colon cancers as a gradual increase in IGF-1 …
levels … 1 (IGF1) and estrogens is correlated with colon cancers as a gradual increase in IGF-1 …
Estrogen receptors in human nontarget tissues: biological and clinical implications
DR Ciocca, LM Vargas Roig - Endocrine reviews, 1995 - academic.oup.com
… the study of estrogen receptor(s) (ER) and estrogen-regulated proteins in breast cancer. At
that … In the cytoplasm E may bind to low affinity binding (LAB) proteins. Once in the nucleus, E …
that … In the cytoplasm E may bind to low affinity binding (LAB) proteins. Once in the nucleus, E …
[PDF][PDF] Estrogen receptor beta in colorectal cancer prevention: Do we have conclusive proof
M Barone, A Di Leo - J Genet Syndr Gene Ther, 2013 - academia.edu
… role of estrogens on CRC and colonic adenomatous polyps. Such … Estrogen Receptors (ERs),
estrogen receptors alpha (ER-α) and … sex steroid receptors can activate intracellular kinase …
estrogen receptors alpha (ER-α) and … sex steroid receptors can activate intracellular kinase …
Oestrogen and progesterone receptors in colorectal cancer and human colonic cancer cell lines
CW Hendrickse, CE Jones, IA Donovan… - British journal of …, 1993 - Wiley Online Library
… malignant and normal colorectal tissue and in five human colonic cancer cell lines, … cytosolic
estrogen receptors in human colonic carcinoma and in surrounding noncancerous colonic …
estrogen receptors in human colonic carcinoma and in surrounding noncancerous colonic …
Mechanisms for estrogen receptor expression in human cancer
H Hua, H Zhang, Q Kong, Y Jiang - Experimental hematology & oncology, 2018 - Springer
… The unliganded ER has been shown to be present in a cytosolic complex with hsp90 and …
hsp90 complex, receptor dimerisation, nuclear localisation and binding to estrogen response …
hsp90 complex, receptor dimerisation, nuclear localisation and binding to estrogen response …
Estradiol activation of human colon carcinoma-derived Caco-2 cell growth
… The amount of estradiol receptor in subconfluent Caco-2 cells… Estradiol receptor was also
assayed by hormone binding to … When the estradiol binding of cytosol protein was analyzed …
assayed by hormone binding to … When the estradiol binding of cytosol protein was analyzed …
Loss of estrogen inactivation in colonic cancer
MA English, KF Kane, N Cruickshank… - The Journal of …, 1999 - academic.oup.com
… expression of sex hormone receptors in gastrointestinal tumors and cell lines, although
the reported levels of estrogen receptors (ER) and progesterone receptors seem to vary …
the reported levels of estrogen receptors (ER) and progesterone receptors seem to vary …
Oestrogen receptors and microsatellite instability in colorectal carcinoma patients
M Notarnicola, R Gristina, C Messa, F Cariola… - Cancer letters, 2001 - Elsevier
… to colorectal carcinoma which involves a mismatch repair deficiency. Oestrogen receptorial
… We considered 1.0 fmol/mg of cytosolic protein as the cut-off for high or low ER levels. The …
… We considered 1.0 fmol/mg of cytosolic protein as the cut-off for high or low ER levels. The …
Estrogen receptors and human disease
BJ Deroo, KS Korach - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
… intracellular … human colon tissue, as well as several human colon cancer–derived cell lines
(28–31). ERβ protein levels are reportedly lower in colon tumors compared with normal colon …
(28–31). ERβ protein levels are reportedly lower in colon tumors compared with normal colon …