… In the present study, we engineered a human cortical NSC line to produce increased levels
of IGF-I to establish an enhanced and multifaceted cellular therapy for AD. IGF-I is a potent …

… with Alzheimer’s disease pathology. We examined postmortem tissue from individuals with
the hallmark lesions of Alzheimer’s disease … of selenoprotein P with Alzheimer’s pathology. …

… human cardiovascular system is regulated by a cortical network comprised of the insular cortex
(… Alzheimer disease (AD) affects the Ic at a preclinical stage. The pathology of AD at the Ic …

… of cortical arteries affects the distribution of Aβ in the cortical parenchyma and in … cortical
blood vessel walls. The hypothesis that CVD inhibits the elimination of Aβ from the aging human …

… expressed in the Alzheimer disease, but not in normal human brain tissue. We found that
α1 laminin was heavily over-expressed in Alzheimer disease frontal cortex, and localized in …

… frontal cortex area 8 at advanced stages of Alzheimer’s disease … to the ribosome in frontal
cortex at terminal stages of AD which … models do not apply to real human disease counterparts. …

… autopsy tissue from the entorhinal cortex of control and AD … Alzheimer’s disease and
compared it to PHF and plaque distribution. We have also characterized a novel antibody for human …

… the SVZ/cerebral cortex of adult mice and in human cortical NPC in … derived from human
embryonic cerebral cortex showed that Aβ … of differentiating human cortical neurospheres to Aβ …

… Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third
… recognition of Alzheimer's disease and the distribution pattern of cortical changes related to …

… Alzheimer's disease (AD). Less well studied are the actual synaptic connections of affected
areas of the brain, such as the cerebral cortex. … and V of human frontal cortex (Brodmann area …