Staging of Alzheimer-related cortical destruction

H Braak, E Braak, J Bohl - European neurology, 1993 - karger.com
… Fischer P: Alz heimer lesions in the entorhinal region and isocortex in Parkinson's and
Alzheimer's disease. Ann NY Acad Sci 1991 ;640:203-209. 26 Braak H, Jellinger K. …

MicroRNA: implications for Alzheimer disease and other human CNS disorders

OC Maes, HM Chertkow, E Wang… - Current …, 2009 - ingentaconnect.com
Understanding complex diseases such as sporadic Alzheimer disease (AD) has been a
major challenge. Unlike the familial forms of AD, the genetic and environmental risks factors …

Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex

DG Walker, AM Whetzel, G Serrano, LI Sue… - Neurobiology of …, 2015 - Elsevier
… reduced risk of developing Alzheimer's disease (AD). … disease groups. However, increased
expression of CD33 mRNA was associated with increasing AD pathology in temporal cortex

[图书][B] The cytoskeleton in Alzheimer disease

RD Terry - 1998 - Springer
… Most investigators of Alzheimer disease (AD) seem … the Alzheimer-like changes (Podlisny
et aI., 1993). A cognitively normal elderly human may have a high concentration of cortical

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex

G Gasparoni, S Bultmann, P Lutsik, TFJ Kraus… - Epigenetics & …, 2018 - Springer
… Given this high agreement, we conclude that NeuN-based cell separation from human
cortical postmortem samples is a robust and reproducible approach, even across brain regions …

Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease

JL Price, AI Ko, MJ Wade, SK Tsou… - Archives of …, 2001 - jamanetwork.com
… The average number of neurons (A) and tissue volume (B) in the entorhinal cortex as a whole
and in layer II alone in the healthy nondemented, preclinical Alzheimer disease (AD), and …

The autonomic-related cortex: pathology in Alzheimer's disease.

CC Chu, D Tranel, AR Damasio… - … cortex (New York, NY …, 1997 - academic.oup.com
Alzheimer's disease (AD) causes progressive deterioration of cognition and behavior.
Memory dysfunction is the hallmark, but there are also changes in behavior, emotion and …

[HTML][HTML] Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease–like transgenic mouse models

JL Frost, KX Le, H Cynis, E Ekpo… - The American journal of …, 2013 - Elsevier
Human cortical and hippocampal brain blocks were fixed in 10% neutral buffered formalin
for 2 hours (brief fixation) with the exception of one DS brain that was fixed for multiple years (…

β‐Secretase‐1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal …

Y Cai, K Xiong, XM Zhang, H Cai… - European Journal of …, 2010 - Wiley Online Library
… in aged monkey and AD human cerebral cortex. Western blot … in plaque‐bearing human
and monkey cortex relative to controls. … in AD but not in control human cortex, with a trend for …

Evidence for a membrane defect in Alzheimer disease brain.

RM Nitsch, JK Blusztajn, AG Pittas… - Proceedings of the …, 1992 - National Acad Sciences
… whether neurodegeneration in Alzheimer disease brain is … cortical areas from postmortem
brains of Alzheimer disease … in all examined Alzheimer disease brain regions. The activity …