… which are regulated by NF-κB and disease states which are associated with constitutive
activation of the NF-κB pathway. Strategies to … NFκB levels are elevated in both synovial biopsy …

… this Perspective series indicate that NF-κB is a primary effector of human disease. For this
… safe inhibitors of NF-κB to be used in treatment of both chronic and acute disease situations. …

… , is involved in many human and animal diseases, especially ones associated with chronic
… review describes human diseases in which mutations in the components of the core NF-κB …

… -6, might in part have similar effects, although this remains to be shown in animal models
and human disease. Moreover, these molecules may not be essential for NF-κB activation. …

… NF-κB is constitutively activated in many human cancers, immune disorders, inflammation,
and metabolic diseases, targeting NF-κB … treatment of many human diseases. Experimental …

… of human diseases, including asthma, atherosclerosis, AIDS and diabetes, alzheimer’s disease
… and to review information that implicates NFkB in the pathogenesis of human diseases. …

… of the main human diseases which are initiated due to NF-κB … targeted to interfere with the
NF-κB pathway is provided. This … inhibitors targeting the complex NF-κB pathway at several …

… A large body of recent research suggestsinhibition of NF-κB blocks inflammation, cancer …
other diseases. The enormous potential for thetreatment of disease by inhibiting NF-κB lead to …

… At this point, the key to understanding the roles of NF-κB in human diseases is to identify …
upstream of NF-κB. Defects in these genes are likely to cause various human disorders with …

… NF-κB pathway, and the role of NF-κB activation in the modulation of oxidative stress. A greater
understanding of the complex interplay between the NF-κB … myriad of human diseases for …